18 Endocrine System Pathology Flashcards Preview

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Flashcards in 18 Endocrine System Pathology Deck (19):
1

goiter

enlargement of the thyroid - lack of iodine in the diet = low T3 and T4 levels

2

hyperthyroidism

overactivity of the thyroid gland, thyrotoxicosis (grave disease) increase hr, high body temp, hyperactivity, weight loss, exopthalmos

3

hypothyroidism

underactivity of the thyroid gland. myxedema, cretinism

4

thyroid carcinoma

cancer of the thyroid, removal is normally necessary

5

hyperparathyroidism

excessive production of parathormone - hypercalcemia occurs and cause damage to kidneys and hear, bones become weak, kidney stones

6

hypoparathyroidism

deficient production of parathyroid hormone - hypocalcemia = muscle and nerve weakness, muscle spasms (tetany)

7

adrenal virilisim

excessive secretion of adrenal androgens - females get male like characteristics

8

cushing syndrome

group of s/s produced by excess cortisol from the adrenal cortex - obesity, full face, buffalo hump, hyperglycemia, hypernatremia, hypokalemia, excess ACTH or tumor - to much use of cortisone like drugs

9

addison disease

hypofunctioning of the adrenal cortex low aldosterone and cortisol blood levels

10

pheochromocytoma

benign tumor of the adrenal medulla; tumor cells stain a dark or dusky (phe/o), tumor cells produce excess secretion of spinephrine and norepinephrine

11

hyperinsulinism

excess secretion of insulin causing hypoglycemia

12

diabetes mellitus (DM)

lack of insulin secretion or resistance of insulin in promoting sugar, starch, and fat metabolism in cells, type I is AI, Type II different inheritance

13

secondary complication of diabetes

stroke, retinopathy, glaucoma and cataracts, atherosclerosis, nephrpathy, neuropathy, gangrene

14

acromegaly

hypersecretion of GH from the ant pit after puberty, leading to enlargement of extremities

15

gigantism

hypersecretion of GH from the ant pit before puberty, leading to abnormal overgrowth of body tissues

16

dwarfism

congenital hyposecretion of GH; hypopituitary dwarfism

17

panhypopituitarism

deficiency of all pituitary hormones

18

syndrome of inappropriate ADH

excessive secretion of antidiuretic hormone

19

diabetes insipidus (dI)

insufficient secretion of ADH (vasopressin)

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