20. hepatozelluläres Karzinom Flashcards by Ian Paglione

Q

(HCC)

Epidemiologie

A

Häufigkeitsgipfel in Europa zw. 50-60 Lj.

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Q

(HCC)

Hauptrisikofaktor

A

Leberzirrhose

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Q

(HCC)

Differenzialdiagnose

A

Lebermetastasen

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Q

(HCC)

Lebermetastasen: Diagnostik

A

Sonografie der Leber

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Q

(HCC)

Lebermetastasen: sonografischer Befund

A

“Bull’s eye”

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Q

(HCC)

“Bull’s eye”

A

echoreiche, solide Metastase mit echoarmem Randsaum

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Q

(HCC)

Leitsymptom

A

unspezifische Oberbauchschmerzen

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Q

(HCC)

Labordiagnostik

A

Parameter der Leberzellschädigung
Syntheseparameter der Leber
Screening und Verlaufsparameter

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Q

(HCC)

Parameter der Leberzellschädigung (2)

A

↑ Transaminasen; GLDH

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Q

(HCC)

Transaminasen (2)

A

ALT/AST

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Q

(HCC)

Syntheseparameter der Leber

A

↓ Quick-Wert; Albuminm; Cholinesterase

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Q

(HCC)

Screening und Verlaufsparameter

A

AFP

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Q

(HCC)

AFP

A

α1-Fetoprotein

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Q

(HCC)

Bildgebung: Planung

A

Sonografie der Leber
KM-MRT

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Q

(HCC)

MRT-Befunde (2)

A

arterielles Hyper-Enhancement
venöses Hypo- bis Iso-Enhancement

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Q

(HCC)

Therapiemöglichkeiten (5)

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A

Resektion
Lokalablation
interventionelle Therapie
Systemtherapie
Lebertransplantation

Q

(HCC)

Lokalablation: Möglichkeiten

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A

RFA
MWA
Hochpräzisionsradiotherapie

Q

(HCC)

RFA

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A

Radiofrequenzablation

Q

(HCC)

MWA

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A

Mikrowellenablation

Q

(HCC)

interventionelle Therapie: Möglichkeiten (2)

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A

TACE
TARE

Q

(HCC)

TACE

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A

Transarterielle Chemoembolisation

Q

(HCC)

TARE

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A

Transarterielle Radioembolisation

Q

(HCC)

Systemtherapie: Möglichkeiten (2)

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A

AK-Kombinationstherapie
TKI

Q

(HCC)

TKI

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A

Tyrosinkinaseinhibitoren