4-3 Paramyxo

Question 0

Slam is also known as

Answer 0

Cd150

Question 1

Measles H can bind to what cell?

Answer 1

Cd46 and cd150

Question 2

Slam regulates _______ responses

Answer 2

TH1 and TH2

Question 3

Major internal protein

Answer 3

Nucleoprotein

Question 4

Associated with NP

Answer 4

L and P ( polymerase phosphoprotein)

Question 5

Transmembranous envelope glycoprotein

Answer 5

F and H

Question 6

Inside virion envelope

Answer 6

Matrix

Question 7

Part of trabscription complex

Answer 7

Phosphoprotein polymerase

Question 8

Measles Rash is caused by what cells?

Answer 8

T cells

Question 9

Sequelae in cns resulting frkm development of defective mutants

Answer 9

Sspe

Question 10

Persistent infection w/o lysis can occur in what cells?

Answer 10

Human brain cells

Question 11

What happens after inoculation in the respi tract

Answer 11

Local replication

Question 12

Acts as a slow virus and causes sx and cytopath effect in neurons years after

Answer 12

Sspe

Question 13

T cell deficient children have atypical presentation

Answer 13

Giant cell pneumonia w/o rash

Question 14

Interferon a and b activates what?

Answer 14

NK cells

Question 15

What IL is depressed in measles?

Answer 15

IL12

Question 16

Can be administered after exposure

Answer 16

Immmunoglobulin

Question 17

Transmission of measles

Answer 17

Large droplets

Question 18

Measles most infectious at what stage

Answer 18

Prodrome

Question 19

Prodrome starts w?

Answer 19

High fever
4Cs
Photophobia

Question 20

Most commonly seen in the buccal mucosa, other mucous membranes

Answer 20

Koplik spots

Question 21

Clinical consequences of measles

Answer 21

MAPS:
Measles
Atypical
PME
SSPE

Question 22

Rashes prominent in distal areas

Answer 22

Atypical measles

Question 23

Serious complication of measles accounts for 60% deaths

Answer 23

Pneumonia

Question 24

Occured in people who recrived older inactivated vaccines

Answer 24

Atypical

Question 25

Recommended specimens for measles

Answer 25

Respi secretions Urine Blood Brain

Question 26

What Ig is detected greatly at prodrome

Answer 26

IgM

Question 27

Current vaccine used

Answer 27

Schwart or moraten

Question 28

People who should not receive mmr?

Answer 28

Pregnant Immunosuppresed Gelatin/myocin

Question 29

Reduces high risk of measle mortality

Answer 29

Vit A

Question 30

Mumps vaccine?

Answer 30

Jeryl lynn strain

Question 31

Mild coldlike symptoms

Answer 31

Para influenza virus

Question 32

Types 1-3 causes?

Answer 32

Second only to rsv to cause severe lower rti

Question 33

Type 4 causes?

Answer 33

Mild UPPER respi infection

Question 34

Para influenza especially assoc with

Answer 34

CROUP

Question 35

Unlike measles parainfluenza rarely cause

Answer 35

Viremia

Question 36

CMI in parainfluenza causes what?

Answer 36

Both cell damage and protection

Question 37

T or f? Reinfection in parainfluenza

Answer 37

True, milder

Question 38

T or f? Parainf induced protective immunity that is long lived

Answer 38

False

Question 39

A para influenza in infants most notably cause

Answer 39

Croup

Question 40

Subglottal swelling which may close the airway

Answer 40

Croup

Question 41

Principal ddx is epiglotitis by Hib

Answer 41

Parainfluenza

Question 42

Specimen for parainfluenza

Answer 42

Nasal washings and respi secretions

Question 43

To determine specific serotype of parainfluenza

Answer 43

HIB test

Question 44

Method of choice to detect parainfluenZa

Answer 44

Rt pcr

Question 45

Mumps most closely associated to?

Answer 45

Parainf type 2

Question 46

How is the parotid gland infected?

Answer 46

Way of stensens duct | Viremia

Question 47

T or f? In mumps, viremia occurs.

Answer 47

T

Question 48

Where are the sites of viremia

Answer 48

``` Testes Ovary Pancreas Thyroid Etc ```

Question 49

Transmission of mumps?

Answer 49

Direct person to person; | Rspiratory droplets

Question 50

T or f? Swelling of other glands may occur without parotitis

Answer 50

T

Question 51

Virus may cause asymptomatic shedding

Answer 51

Mumps

Question 52

How to confirm diagnosis of mumps?

Answer 52

Serology, 4fold increase in igM

Question 53

Rsv is the Most common cause of

Answer 53

Fatal acute respiratory infrction

Question 54

T or F? Maternal antibody protects infant from infection

Answer 54

F

Question 55

Necrosis of bronchi which leads to formation of plugs

Answer 55

Rsv

Question 56

T or F? Rsv epidemic occur every year

Answer 56

True!! Unlike influenza!!

Question 57

Can also be transmitted by fomites

Answer 57

RSv

Question 58

Infants w rsv

Answer 58

Lrti

Question 59

Modes of control of rsv

Answer 59

Immuno globulin; | Aerosol ribavirin

Question 60

Clinical cnsequence of rsv

Answer 60

Bronchiolitis/pneumonia; Febrile rhinitis and pharyngitis; Common cold

Question 61

Only virus diff to culture

Answer 61

RSv | And metapneumo

Question 62

New paramyxo

Answer 62

Nipah and hendra