4-1 Orthomyxo

Question 0

Subtypes are dt antigenic variations of surface glycoproteins

Answer 0

HA

NA

Question 1

Antigenically stable

Answer 1

Type C

Question 2

LRTI caused by?

Answer 2

Abc
Rsv
Parainfluenza

Question 3

Proteins of ortho

Answer 3

9 sp

1nsp

Question 4

CAuses highly infectious viral illness

Answer 4

Orthomyxo

Question 5

Found in mosquitoes, ticks, and banded mongoose

Answer 5

Thogotovirus

Question 6

7 segments?

Answer 6

C

Question 7

Enveloped?

Answer 7

Yes

Question 8

For Release of virus

Answer 8

Neuraminidase

Question 9

For Core receptor

Answer 9

Nucleoprotein

Question 10

Protein For attachment

Answer 10

Hemaglutinin

Question 11

For regulation of mrna splicing

Answer 11

Ns1 ns2

Question 12

Antiviral drugs target what?

Answer 12

M2 protein

Question 13

Target of neutralizing antibodies

Answer 13

Hemagglutinin

Question 14

Ha causes antigenic changes of what?

Answer 14

Minor drift

Major shift

Question 15

Describe the receptor for HA

Answer 15

Trisaccharide of sialic, gal, glu

Question 16

Neuraminidase is important in determination of what?

Answer 16

Subtypes!

Question 17

THGSY is?

Answer 17

Standard nomenclature

Question 18

Human and animal strains

Answer 18

A

Question 19

Human and swine

Answer 19

C

Question 20

Ha has ? Subtypes?

Answer 20

15

Question 21

Hiw many subtypes of ha and na recovered in humans

Answer 21

4ha

2 na

Question 22

H5n1?

Answer 22

Chickens to humans

Question 23

Shift or drift?
New subtype
Minor
Pandemic

Answer 23

Shift
Drift
Shift

Question 24

Transmission

Answer 24

Inhalation

Question 25

Survives what?

Answer 25

``` Slow drying Dust 4c Seawater -70c ```

Question 26

Systemic sx?

Answer 26

Dt interferon and lymphokines

Question 27

Local sx?

Answer 27

Cilia and mucus secreting cells

Question 28

Important for future protection against infection

Answer 28

Antibody

Question 29

Important cause of croup in children Under 1yo

Answer 29

A

Question 30

Gastric flu. Type?

Answer 30

B

Question 31

Afebrile urti. Type?

Answer 31

C

Question 32

Croup is associated with what sx?

Answer 32

Otitis media

Question 33

Lung complications?

Answer 33

PRimary inf pneumonia Bacterial pneumonia Cardiac involvment Neuro (GBS, reyes, enceph)

Question 34

Sequelae that Affects 2-6yo?

Answer 34

Reyes

Question 35

Reyes manifestations

Answer 35

``` hHiME Hepato Hypogly Mental stat Inclease bloood ammonia Enceph ```

Question 36

Immunity important?

Answer 36

IgA IgG | Celular immunity

Question 37

Antibodies to this is the only way to be protective

Answer 37

Ha and na, others are not

Question 38

T or f? No cross protection to the types?

Answer 38

T

Question 39

Samples best Obtained at what time?

Answer 39

3 days after onset

Question 40

Detects hemadsorbing virus

Answer 40

Hemadsorption

Question 41

Detects virus antigens

Answer 41

Hsf elisa

Question 42

M2 ion channel inhibitors

Answer 42

Rimantidine

Question 43

Ineffective against b and c

Answer 43

A..amantadine