Picorna

Question 0

6 genera (ERHPAC)

Answer 0

Enterovirus
Rhinovirus
Hepatovirus
Parecho
Aphtho
Cardio

Question 1

One of the first viruses to be identified

Answer 1

Foot and mouse disease virus

Question 2

4 major groups of human pathogens

Answer 2

Entero
Rhino
Hepatovirus
Parecho

Question 3

Most serious disease vy any enterovirus

Answer 3

Poliomyelitis

Question 4

Genus of humen entero

Answer 4

Poliovirus (1-3)
Cox A 1-24
Cox B 1-6
Echo 1-33
Entero 68-78
Entero 79- 101

Question 5

Most rhinovirus can br recovered only in human cells at what temp?

Answer 5

33C

Question 6

Originally classified as enterovirus 72

Answer 6

Hep A

Question 7

Previously echo 22 and 23

Answer 7

Parechovirus

Question 8

Encephalomypcarditis of rodents

Answer 8

Cardiovirus

Question 9

Foot and mouth disease of cattle

Answer 9

Aptho

Question 10

Contains genome linked protein

Answer 10

VPg

Question 11

The 5’ longer end has a cloberleaf structure called?

Answer 11

IRES

Question 12

Surface capsid proteins

Answer 12

VP1 and VP

Question 13

Internal protein

Answer 13

VP4

Question 14

Rhino or entero?
Acid stable
1.4 bouyancy
Stabilized by mgcl2

Answer 14

Entero
Rhino
Both

Question 15

Enteroviruses are stable in ether , organic solvents since they do not contain ______ in their capsids

Answer 15

Lipids

Question 16

Antibodies for entero appear the same when____

Answer 16

Symptoms appear

Question 17

At what tissue does entero continue to replicate even high titers of antibody?

Answer 17

GIT

Question 18

Polio viruses are inactivated by?

Answer 18

Heat and chlorine

Question 19

Primary multiplication of polio

Answer 19

Oropharhngeal

Intestinal mucosa

Question 20

Transmission and portal of entry?

Answer 20

Fecal oral

Mouth

Question 21

Most common form of polio

Answer 21

Mild/abortive poliomyelitis

Question 22

Present as stiffness in be back and neck

Answer 22

Nonparalytic/aseptic

Question 23

Pm Flaccid paralysis?

Answer 23

Paralytic

Question 24

Muscle wasting

Answer 24

Progressive post PM muscle atrophy

Question 25

Rarely used dx for polio

Answer 25

Serology!!

Question 26

Used for who eradication of polio campaign

Answer 26

OPV

Question 27

2 groups of coxsackie

Answer 27

A and B

Question 28

Most frequent serotype of group a cox

Answer 28

A9

Question 29

Diffuse myositis with necrosis of fibers of voluntary muscles (causing flaccid paralysis)

Answer 29

COx A

Question 30

Diseases of cox A

Answer 30

Herpangina Hand foot and mouth disease Acute hemorrhagic conjunctivitis

Question 31

Most commonly identified causative agebts of viral heart disease in humans

Answer 31

Cox B

Question 32

Diseases of Cox B

Answer 32

Pleurodynia Myocarditis Perocarditis Severe generalized ds of infants

Question 33

Known as epidemic myalgia

Answer 33

Pleurodynia

Question 34

Known as vesicular pharyngitis

Answer 34

Herpangina

Question 35

Aseptic meningitis iS caused by all types of

Answer 35

Group a | Most common 7 and 9

Question 36

Abrupt onset of fever and sore throat, hyperemix pharynx vesicles on the post half of palate

Answer 36

Herpangina

Question 37

Ulcerations in herpangina is found in the

Answer 37

Posterior pharyngeal wall

Question 38

Vesicular rash on the palm and sole

Answer 38

Hand foot mouth ds

Question 39

HfmD ia caused by?

Answer 39

Cox A16

Question 40

Stabbing pain preceded by headache, anorexia, malaise; chest pain intensified by movt.... Caused by what?

Answer 40

Cox B

Question 41

Usually cause by a24 and entero 70

Answer 41

Acute hemorr conjunctivitis

Question 42

Enterovirus antigenically related to B5

Answer 42

Swine virus

Question 43

Meaning of echo virus

Answer 43

Enteric Cytopathogenic Human Orphan

Question 44

Method of choice for isolation of ECHO

Answer 44

Monkey kidney cell culture

Question 45

Disease associated with ecHO

Answer 45

Aseptic meningitis Rashes Exanthem Infantile diarrhea

Question 46

One of the main causes of cns disease

Answer 46

Entero 71

Question 47

Isolated in px w broncholitis

Answer 47

Entero 68

Question 48

Only cox B may cause

Answer 48

Diabetes/pancreatitis; | Pleurodynia

Question 49

Only cox a may cause?

Answer 49

Herpangina | Conjunctivitis

Question 50

Cox a, b and echo may cause?

Answer 50

Rash/ exanthem

Question 51

Neonatal ds obly cause by?

Answer 51

B and echo

Question 52

Consists of 6 types, others originally from echo; highly divergent with almost no protei identical to other picorna

Answer 52

Parecho

Question 53

Common cold viruses

Answer 53

Rhino

Question 54

Early symptom of colds

Answer 54

Chilliness

Question 55

Cause foot and mouth ds

Answer 55

Apthovirus

Question 56

Aphtho is acid labile at?

Answer 56

Ph below 7 (wow generAl talaga!)

Question 57

Causes in encep and myocarditis in RODENTS

Answer 57

Cardio

Question 58

Consists of 2 virus

Answer 58

Emcv (1 serotype) | Theilovirus

Question 59

True or false? Emcv results in cns involvement but NO myocarditis

Answer 59

True!!