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Flashcards in 4B-5 Filo Deck (12)
0

Two known filo that are antigenically distinct

Marburg
Ebola

1

4 subtypes of ebola

Sir z
Sudan
Ivory coast
Reston
Zaire

2

4 subtypes differ only by___%

40

3

Genome of filo?

RENN
Rna ENVELOPED negative strand nonsegmented

4

Evelope GP is encoded how?

2 reading frames and become trimer spikes!

5

T or F?Infections from these tend to be immunosuppressive?

T

6

How are filo deactivated

Heat 30 mins 60.C
UV and gamma rad
Lipid solvent
Bleach and phenolics

7

Tropism for?

Immune response cells

8

Resevoir host of marburg and ebola

Rodent/bat

9

Aftican hemorrhagic fever seen w?

Marburg and ebola

10

Subtype that possess low pathogenicity to humans

Reston

11

T or F? Filo can be cultured in cell lines

T