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Flashcards in Polyoma And Deck (26)
0

E6 binds to?

P53

1

E7 binds to?

P105rb

2

What is infected w warts?

Squamous epithelium

3

What happens when mucous membranes are infected

Genital
Oral
Conjuctival papilloma

4

Char of HPV infections

Koilocytes

5

Important for control and resolution of hpv infectns

Innate
CMI

6

High risk hpv types

16
18

7

Oncogenes of high risk hpv

E5-7

8

Site of immunogically privileged

Terminally differentiated cell (dead cell)

9

T or f? Hpv can be transmitted by fomites

True

10

hpv is acquired thru

Vertical transmission
Sex
Direct
VSD

11

T or f? Old aged adults are prone to laryngeal papilloma

False, middle

12

All mucosal syndromes have what type except CIN

6,11

13

Common wart types

2,4

14

All other types found in what skin wart?

Epidermodysplasia verruciformis
EV

15

Flat wart types?

3,10

16

Warts can be confirmed histo what are seen?

Hyperplasia of pickle cells
Xs keratin

17

T or f? culture relevant in HPV

False

18

Tx that stimulates innate and inflammatory responses

Imiquimod
Interferon

19

Tx to treat hpv infected cells

Cidofovir

20

In hpv pap smeArs can replace vaccines tor f

F

21

Less prevalent polyoma

Bi
Wu
Merkel cell

22

Prototype of polyoma

Sv40

23

Encoded for non structural proteins of polyoma

Early

24

Late region codes for?

Capsid proteins-vp1,2,3

25

Noncoding region contains

OriC
Control sequence for early and late