medicine and science Flashcards

1
Q

What is the scientific method

A
  • observation/experiments
  • explanation (hypothesis) which can be tested
  • prediction
  • experimentation and data interpretation
  • confirmation (or not) of the hypothesis
  • peer review
  • publication (conference/academic journal)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are some funding bodies towards research

A

pharmaceutical industry
government
charities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

example of marketed antiviral drug

A

tamiflu

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What can lead to ‘bad science’

A
under recruitment in trials 
no published protocols 
placebo capsules contained in dehyrocholic acid and dibasic calcium phosphate dehydrate 
unidentifiable authors 
missing statistical analyses
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

tell me about Pfizer

A

was said to treat a range of neurological disorders such as bi solar epilepsy migraines e.t.c

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What a primary research study

A

direct experimentation:
-in vitro models (molecular biology, cell and tissue culture, isolated tissue and organs
-in vivo testing (animals and volunteers (artificial control over biological variables)
clinical trials:
drug treatments and follow up
surveys

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

secondary research study

A
  • review (expert summery of a number of research studies)
  • systematic review (objective analysis of all qualifying primary research studies
  • meta-analysis-integrated analysis of the numerical data from all qualifying studies
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

evidence pyramid

A

randomised control trail is the peak as very reliable whereas an ‘expert opinion’ or meeting someone at the union may be biased

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

peer review

A

this is the process of subjecting an authors scholarly work or ideas to scrutiny of anonymous referees who are experts in the field

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what does peer review ensure

A

authors meet the standards of their discipline and of science generally

How well did you know this?
1
Not at all
2
3
4
5
Perfectly