ABNORMALITIES IN CELL GROWTH Flashcards

(44 cards)

1
Q

Abnormalities in Cell Growth

A

A. Retrogressive
B. Progressive
C. Degenerative

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2
Q

RETROGRESSIVE (2)

A

Development defects
Atrophy

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3
Q

Development Defects

A

Hypoplasia
Aplasia
Agenesia
Atresia

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4
Q

• The organs or a part of the tissue is smaller than normal.

A

RETROGRESSIVE

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5
Q

Incomplete development of the organ

A

Aplasia

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6
Q

Failure of an organ to develop fully

A

Hypoplasia

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7
Q

Failure of an organ to form an opening

A

Atresia

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8
Q

o Acquired decrease of the size of a normally developed organ

A

Atrophy

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9
Q

PROGRESSIVE

A

Hypertrophy
Hyperplasia

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10
Q

The tissue has an increase in size due to the increase in size of the individual cells

A

Hypertrophy

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11
Q

The tissue has an increase in the number of cells

A

Hyperplasia

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12
Q

• There is change due to aberrations of cellular growth patterns

• There is disturbance during the pattern of development

A

DEGENERATIVE

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13
Q

There are four categories of DEGENERATIVE

A

Dysplasia
Metaplasia
Anaplasia
Neoplasia

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14
Q

• Means “disordered growth”

A

Dysplasia

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15
Q

Presence of abnormal cells within a tissue (reversible)

A

Dysplasia

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16
Q

• Reversible
• It involves of transformation of one type of adult cell to another

A

Metaplasia

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17
Q

Lack of differentiation of cells

irreversible

A

Anaplasia

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18
Q

Neoplasia means

19
Q

• Uncontrolled proliferation of cells with no purpose

20
Q

• Mass of neoplastic cells

A

Tumor/Neoplasm

21
Q

General Characteristics Of Tumors

A

• May resemble and function like a normal cell

• Autonomous

• Parasitic nature

22
Q

• Non-responsive to normal growth factors

23
Q

Competes with cells for metabolic needs

A

Parasitic nature

24
Q

Parts of Tumor

A

Parenchyma
Stroma

25
actively dividing • Darkly stained An active element of the tumor
Parenchyma
26
The connective framework with the lymphatic or vascular channels
Stroma (body)
27
DEATH CLASSIFICATION OF TUMOR Benign: Malignant:
Usually not cause death Usually causes death
28
DIFFERENTIATION CLASSIFICATION OF TUMOR Benign: Malignant:
Well-differentiated Some lack of differentiation
29
RATE OF GROWTH CLASSIFICATION OF TUMOR Benign: Malignant:
Progressive and slow Erratic
30
METASTASIS CLASSIFICATION OF TUMOR Benign: Malignant:
Absent Frequent
31
EPITHELIAL TISSUE GENERAL TUMOR NOMENCLATURE Benign: Malignant:
-oma -carcinoma
32
CONNECTIVE TISSUE GENERAL TUMOR NOMENCLATURE Benign: Malignant:
- oma - sarcoma
33
• Monstrous tumors Benign type of tumor It can grow on any part of the body
Teratoma
34
• Attempts to establish an estimate of the level of malignancy of a tumor
Grading of Tumors
35
Grading of Tumors Based on cytologic differentiation of_______ and ______
tumor cells and number of mitoses
36
cytologic differentiation of tumor cells
Well-differentiated Undifferentiated
37
• Tumor cells resemble normal cells
Well-differentiated
38
• Tumor cells do not resemble normal cells
Undifferentiated
39
• For the size of the tumor • Extent of the spread of the cancer cells to the lymph nodes • Presence of metastasis
staging
40
Used to classify the grading of tumors
BORDER'S CLASSIFICATION OF TUMOR
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BORDER'S CLASSIFICATION OF TUMOR Differentiated Cells Grade l ll lll lV
Grade l 100-75 ll 75-50 lll 50-25 lV 25-0
42
BORDER'S CLASSIFICATION OF TUMOR Undifferentiated Cells Grade l ll lll lV
Grade l 0-25 ll 25-50 lll 50-75 lV 75-100
43
Limitations of Grading
• It is subjective • Higher grades of tumor have more tendency to metastasize • Most sarcomas cannot be graded
44
Complete non-appearance of an organ
Agenesia