BIOPSY AND POST MORTEM EXAMINATION Flashcards

(71 cards)

1
Q

Pathology is divided into two major areas:

A

Clinical Pathology
Anatomical Pathology

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2
Q

Histopathology

A

CFITS

Cytology
Frozen Biopsy
Immunohistochemistry/ Immune staining
Tissue Processing
Special Staining

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3
Q

The study of tissues affected by disease

Useful in making a diagnosis and in determining the severity and progress of a condition

A

HISTOPATHOLOGY

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4
Q

Includes all activities done in the laboratory in order to produce a suitable specimen slide for viewing by the pathologist

A

HISTOPATHOLOGIC TECHNIQUES

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5
Q

PROFESSIONALS UNDER HISTOPATHOLOGY

A

Pathologist
Associate Pathologist
Histotechnologist/Histotechnician

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6
Q

(Head of the Laboratory)

A

Pathologist

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7
Q

Sections large and hollow organs to allow fixation down to mounting

Examines the tissue sections, cytologic slides under the microscope

A

Pathologist

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8
Q

o Monitor staff performance
o Pinpoint problematic situations and find solutions

A

Associate Pathologist

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9
Q

Assists the pathologists by providing spx slides that are properly labeled, processed, stained, and mounted

A

Histotechnologist/Histotechnician

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10
Q

o Ensures high quality conditions of equipment, formalin, and other chemicals and reagents

o Analyze problems and corrects them

A

Histotechnologist/Histotechnician

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11
Q

Work systematically to minimize error

A

Histotech

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12
Q

QUALITY IN HISTOPATHOLOGY LABORATORY

A

Quality Assurance

Quality Management Systems

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13
Q

• Ensuring that everything is right (test time, specimen, patient, diagnosis and price)

A

Quality Assurance

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14
Q

• Set of coordinated activities to regulate a lab in order to continually improve its performance

A

Quality Management Systems

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15
Q

Considers pre-analytic, analytic, and post-analytic phase

A

Quality Management Systems

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16
Q


From receiving to specimen accessioning down to mounting


Actual reading of the slides


Releasing of results

A

Pre-analytic

Analytic

Post-analytic

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17
Q

Documents

A

RRAP

Request forms
Reports
Accession Logbooks
Preventive Maintenance

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18
Q

Types of results

A

• Surgical Pathology

• Cytopathology

• Autopsy Report

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19
Q

TAT Surgical Pathology and Cytology =

A

2 days

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20
Q

TAT

Frozen Sections =

A

5-15 minutes

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21
Q

TAT

Autopsy Report =

A

7 days

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22
Q

Reports

A

Patient report
Telephone report
Preliminary report
Final report
Incident report

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23
Q

Post mortem examination

A

Autopsy

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24
Q

Ante mortem examination

A

Biopsy

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25
Autopsia Cadaverum
Autopsy
26
Biopsy "____" - life; "___" - to see
Bio Opsia
27
AUTOPSY • AKA "
Necropsy Post-Mortem Thanatopsy
28
Purposes of autopsy
• Determine the cause of death and extent of injury • Uncovering existence of an undetected disease
29
Types of Autopsy according to:
Purpose Completeness Manner of incision
30
Types of Autopsy according to: (n) • Purpose
Medical/ Hospital Medico-legal
31
Types of autopsy acc to COMPLETENESS
Partial Complete
32
Types of autopsy acc to incision
Y-shaped Straight cut
33
DISSECTION/EVISCERATION TECHNIQUES
GHON ROKITANSKY LETULLE VIRCHOW
34
One by one removal of organs Most widely used
VIRCHOW
35
"In situ" (in place) dissection, followed by en bloc removal
Rokitansky
36
"En bloc" removal Organs of same group/activity/region are removed at the same time
Ghon
37
"En masse" removal of organs All organs are removed at the same, then dissected by blocks
Letulle
38
Prerequisites:
•Written or informed consent from the legal next-of-kin • Medical abstract or clinical data • Autopsy Request (suspicious evidence of foul play)
39
Personnel
CPD Coroner Prosector Diener
40
A public official who is empowered to order an inquest into the manner or cause of death
Coroner
41
• Pathologist who performs the dissection
Prosector
42
Comes from the German word "leichendiener" meaning "servant of the dead"
Diener
43
Diener Comes from the German word "_____" meaning "servant of the dead"
leichendiener
44
Assists during an autopsy, and assumes many and varied responsibilities in the autopsy laboratory
Diener
45
(____= before;____ = death)
ante mortem
46
TYPES OF BIOPSY
Fine needle aspiration Core needle Incisional Excisional Punch Shave Curettage
47
• Simplest, least invasive Minor type of getting tissue sections • Uses very thin needle attached to a syringe to take out a small amount of fluid and tissue from area
Fine needle aspiration
48
• Uses slightly larger needle
Core needle
49
Remove small column of tissue (1/16 inch in diameter, (½ inch long)
Core needle
50
• Surgical • Small part of a large lesion or tumor is taken
Incisional
51
• Surgical • Entire affected area is taken
Excisional
52
• For skin Uses circular blade to obtain deeper skin sample that removes a short cylindrical core of tissue ("apple core")
Punch
53
• For skin • Small fragments of outer layers of skin are "shaved" or scraped
Shave
54
• Tissues are removed from body cavity (or canals) using a currette
Curettage
55
Methods of Examination
Fresh Fixed
56
What are the processes which are performed in histopathologic techniques
Tissue processing Cytology Frozen biopsy Immunohistochemistry Special staining
57
What phase is the tissue processing
Pre analytic
58
Autopsy comes from the GREEK word
Autopsia Cadaverum
59
Ms. Rose kay nag somatic death na. Unsa man ang type of examination of tissue?
AUTOPSY Malamang…
60
Who submits the autopsy request?
Coroner
61
Bone marrow aspiration utilizes
Core needle biopsy
62
Asa gina obtain and bone marrow aspirate?
Iliac crest of hip bone
63
Fresh tissue examination
Teasing Crushing/ Squashing Frozen section Smear preparation
64
Smear preparation
Streaking Spreading Pull-apart Touch preparation
65
Fixed tissue examination
Fixation Decalcification Dehydration Clearing Infiltration Embedding Blocking Trimming Sectioning Staining Mounting Labelling Microscopic examination
66
Bone marrow aspirate examination is done through
Pull-apart
67
Is the tissue in frozen sections fresh??
Yuh
68
Requested during intra-operative procedures to help the surgeon in choosing his next plan of action
Frozen sections
69
Fresh tissues are frozen using a cryostat or freezing microtome ● Can use two types of microtome ● When using these types, the temperature inside should be maintained…
(-10 to -30 degree Celsius)
70
Which has better quality slides? Fresh or Fixed?
Fixed
71
Which histopathologic examination is faster? Fixed or Fresh?
Fresh