Alimentary System Pathology Flashcards Preview

RUSVM Pathology II > Alimentary System Pathology > Flashcards

Flashcards in Alimentary System Pathology Deck (31):
1

Normal oral or gastrointestinal mucosa should look

Smooth and shiny

2

Why is feces considered a window into the health of the alimentary system?

Quality and quantity of the feces is often an early indicator of alimentary dysfunction

3

Portals of entry for pathogens of the alimentary system

Ingestion

Coughed up by lungs and swallowed

Systemic hematogenous route

Migration through the body

4

Defense mechanisms of the alimentary tract

Saliva

Resident flora and fauna

Gastric pH

Immunoglobulins

Vomiting

Intestinal proteolytic enzymes

Phagocytes

High epithelial turnover

Increased peristalsis

5

Oral Cavity Congenital Diseases

Cleft Palate - Palatoschisis

Cleft Lip - Cheiloschisis

Malocclussions

6

Palatoschisis and Cheiloschisis cause

Genetic Disorder

Toxins

Maternal exposure to drugs during pregnancy

7

Palatoschisis

Central defect in the midline fusion of the palatine shelves resulting in communication between the oral and nasal cavity

8

Malocclussions

Failure of the upper and lower incisors to interdigitate properly - results in difficulty in prehension and mastication of food

9

Brachygnathia

Shorter lower jaw

_________________

Inferior vs Superior

10

Prognathia

Protrusion of the lower jaw

11

Oral Cavity: Dental/Peridontal Diseases 

Dental Attrition

Periodontal Disease

12

Dental Attrition

Loss of tooth structure caused by mastication

13

Abnormal wearing of teeth is most common in

Herbivores 

"Step Mouth"

14

Periodontal Disease

Resident bacterial films and the acid and enzymes they produce lead to enamel, gingival and periodontal ligament damage

15

Dental calculus

Mineralized dental plaque

16

Oral Cavity: Diseases of the Tongue

Actinobacillosis - "Wooden Tongue"

Thrush

17

Primary diseases of the tongue are (common/rare)

Rare

____________________

Exception : Actinobacillosis

18

Actinobacillosis causes

chronic stomatitis

19

Splendore-Hoeppli phenomenum

Seen with Actinobacillosis

Radiating clubs of amorphous eosinophilic material

20

Thrush - Candidiasis

Candida spp

Observed in young animals treate with antibiotics for long periods of time

21

Lingual lesions are often manifestation of 

Systemic Disease 

___________________

Ex: Renal Disease, BVD, FMD

22

Etiology of Stomatitis

Infectious agents

Trauma

Chemical Injury

Auto-immune

Idiopathic

23

Clinical signs of Feline Chronic Gingivo-Stomatitis (FCGS)

Oral pain

Dysphagia

Ptyalism

Weight Loss

24

Vesicle

raised lesion filled with clear fluid located within the epithelium or between the epithelium and lamina propria

25

Vesicular stomatitides in dogs could be indicative of

Immune Mediated Disease

26

Vesicular stomatitides in cats are often the result of  

Calicivirus infection

27

Vesicular stomatides in large animals it is important to rule out

Viral diseases

___________________________

Non fatal but result in huge economic loss

28

Pathogenesis of viral vesicular stomatitides

Viral induced epithelial damage → intracellular edema in keratinocytes → vesicles → bullae → rupture → erosion and ulceration

29

Viruses that cause vesicular stomatitis

Foot and Mouth Disease

Vesicular Disease

Vesicular Exanthema of Swine

Swine Vesicular Disease

30

Foot and Mouth Disease clinical signs

Exotic (Foreign) Animal Disease

Drooling, lameness

31

Pathogenesis of Foot and Mouth Disease

Virus ingestion/inhalation → pharynx → viremia → oral mucosa/epidermal sites → lesions develop in areas subjected to mechanical injury.