ANEMIA Flashcards

(43 cards)

1
Q

Conditions under microcytic

A

Sideroblastic anemia
iron deficiency, anemia
anemia of chronic disease,
thalassemia

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2
Q

Conditions under macrocytic

A

Non-megaloblastic,
chronic liver disease,
alcoholism,
aplastic anemia

Megaloblastic
vitamin B12 deficiency
folate deficiency,
myelodysplasia/myelodysplastic syndrome

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3
Q

Conditions under normocytic

A

Increase reticulocyte count,
hemolytic anemia

decrease reticulocyte count
plastic anemia
myeloma
myelofibrosis
neoplasm
Uremia

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4
Q

Normocytic with high reticulocyte count 

A

Hemolytic anemia 

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5
Q

Enzyme deficiency lead to hemolytic anemia during oxidative stress

A

G6PD 

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6
Q

Condition is by ringed in bone marrow 

A

, sideroblastic anemia 

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7
Q

Type of anemia associated with ineffective production due to globin synthesis

A

Thalassemia and hgb E

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8
Q

Consequence of decreased hemoglobin concentration in blood

A

Hypoxia

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9
Q

Iron deficiency anemia in lab findings 

A

low in retic count
low in serum ferritin
low in serum iron
low in transferrin
high in TIBC 

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10
Q

Anemia of chronic disease lab findings 

A

Normal in Retic Count
high in serim ferritin
low in setum iron
low in transferrin
low in TIBC

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11
Q

Sideroblastic anemia lab findings

A

Low in retic
high in ferritin
high in iron
high transferrin
low in TIBC 

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12
Q

Thalasse lab finding

A

High retic
, normal ferritin
normal iron
normal transferrin
normal TIBC 

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13
Q

Parameters that measure different sizes of red blood cell is called

A

Relative distribution width

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14
Q

Decrease in oxygen carrying capacity of blood

A

Anemia

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15
Q

Anemia is decreased in CBC parameters of

A

RBC count
hemoglobin
hematocrit 

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16
Q

Classic symptoms of patient with anemia

A

Fatigue and shortness of breath

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17
Q

Degree of how much oxygen is found in hemoglobin

A

02 saturation or oxygen saturation

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18
Q

If a patient with anemia has oxygen in hemoglobin, it is considered as 

19
Q

If patients having a rapid fall of hemoglobin concentration it has

20
Q

Hemoglobin concentration of moderate anemia

A

7 to 10 g/dl

21
Q

Hemoglobin concentration in severe anemia and produces what symptoms

A

<7g/dl

Tachycardia
hypotension
Volume loss 

22
Q

Severity of anemia is gauge by

A

Degree of reduction in hemoglobin cardiopulmonary adaptation
rapidity of progression in anemia 

23
Q

Anemia caused by sudden loss of blood

A

Increase in heart rate, respiratory rate and cardiac output 

24
Q

Anemia caused by slow loss of blood

A

Decrease hemoglobin oxygen affinity increase 2,3 BPG (bisphosphoglycerate)

25
In rapid blood loss hemoglobin and hematocrit is
Unchanged because of balance loss of plasma
26
In healthy individual with no anemia, how many percent of RBCs are removed
1%
27
Adequate RBC production requires nutritional factors such a
Iron Folate vitamin B12 
28
Term used for narrow, erythroid, proliferative activity
erythropoiesis 
29
Refers to production of erythroid cell that are defective
Ineffective erythropoiesis
30
Ineffective erythropoietsus undergo in bone marrow
Apoptosis 
31
Conditions off ineffective erythropoiesis
Megaloblastic anemia, Sideroblastic anemia thalassemia 
32
Aplastic anemia is
Hypo cellular
33
Myelodysplasia
Hypercellular
34
Refers to decrease number of erythroid precursor cell
Insufficient erythropoiesis 
35
Factors of insufficient erythropoiesis 
Deficiency of iron deficiency of erythropoietin, blood loss/ decrease survivability 
36
Low MCV
Decrease in hemoglobin concentration
37
High MCV
Maturation of nucleus
38
Type of anemia due to defect in nutritional value
Megaloblastic anemia
39
Type of anemia caused by vitamin B12 deficiency
Pernicious anemia
40
Membrane changes owing to disruption of the cholesterol to possible lipid ratio
Non-megaloblastic anemia 
41
Premature destruction, and shortened survival of RBC
Normocytic anemia
42
RDW normal 
Decreased alpha or Beta-thalassemia trait , anemia of chronic disease, hemoglobin E disease  Normal anemia of chronic disease, anemia of renal disease, acute hemorrhage, hereditary spherocytosis 
43
RDW increased
Decrease iron deficiency sickle cell B-thalassemia normal early iron,folate, vitamin B 12 mixed deficiency of iron Sickle cell anemia, hemoglobin SC disease, myelodysplastic syndrome