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HEMA 311 > NON MALIGNANT > Flashcards

NON MALIGNANT Flashcards

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1
Q

Normal range for lymphocytes in adult

A

22 to 40%

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2
Q

If value is less than normal range, it is called

A

Lymphocytopenia

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3
Q

If value is above upper limit, it is called

A

Lymphocytosis

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4
Q

Acute benign and self limiting lymphoproliferative disorder caused by Epstein-Barr virus and observe with fever and lymphadenopathy

A

Infectious mononucleosis

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5
Q

Epstein-Barr virus is also cause of

A

Burkitt lymphoma in Afrikaans children

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6
Q

Natural and normal in infants and children up to 10 years old

A

Lymphocytosis 9×10^9/L

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7
Q

Malignant condition produce lymphocytosis

A

Lymphocytic leukemia,
Leukemic phase of lymphoma
cancer
Waldenstrom

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8
Q

Epstein-Barr virus is a ___ and in infectious mononucleosis it infects what

A

Human herpes dna virus, DNA virus
B-lymphocyte 

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9
Q

Transmitted by close contact with oropharyngeal secretions

A

Ebstein barr virus

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10
Q

In Epstein-Barr virus second wave of seroconversion occurs during

A

Late adolescence (15 to 24 years old)

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11
Q

Incubation period of infectious mononucleosis and it lasts for

A

10 to 50 days

1 to 4 weeks 

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12
Q

Clinical symptoms of infectious mononucleosis

A

Fatigue
Malaise
sore throat
fever
lymphadenopathy
Splenomegaly 50% 

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13
Q

Most common complication of infectious mononucleosis

A

Hepatitis

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14
Q

Antibodies present inpatient with infectious mononucleosis are

A

Heterophil antibodies

EBV antibodies 

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15
Q

In immunosuppressed patient, the EBV infection ranges from

A

35 to 47%

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16
Q

Blood transfusion from an immune donor to a non-immune recipient may produce infection

A

Infectious mononucleosis post perfusion syndrome

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17
Q

Infectious mononucleosis following blood transfusion is caused by

A

Cytomegalovirus infection 

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18
Q

Heterophil negative commonly seen in immunocompromised patients

A

Cytomegalovirus infection

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19
Q

If a patient has a leukocyte count of 10 to 20×10^9/L 

A

Leukopenia 

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20
Q

Classified as member of herpes, family of virus

A

cytomegalovirus infection

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21
Q

Five recognize human herpes viruses

A

Herpes simplex I
herpes simplex II
varicella zoster virus
EBV
CMV

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22
Q

Active CMV infection is a major cause of morbidity and patience with

A

Aids

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23
Q

Most important causes of congenital viral infection

A

Cytomegalovirus infection

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24
Q

Major cause of death, following allogenic bone marrow transplantation

A

Interstitial pneumonitis

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25
Ubiquitous human viral pathogen and is endemic worldwide
Cytomegalovirus infection
26
CMV can be present in
Blood urine breast milk
27
CMV infection is
A symptomatic
28
CMV infected newborns are more prone to develop severe
Cytomegalic inclusion disease
29
Bacterial organism that produces inflammation of an entire respiratory tract causing whooping cough
Bordetella pertussis 100×10^9/L
30
Lymphocytosis in B.pertussis is most evident during 
First 3 weeks of illness, then decreases
31
Protozoal infection acquired from cats
Toxoplasmosis
32
Benign condition in children with leukocytosis
Infectious lymphocytosis
33
 stress induced lymphocyte, reduction associated with administration of corticosteroid
lymphocytopenia
34
Lymphocytopenia is associated with
Granulocytosis
35
Caused by a virus member of Coxsackie group
Infectious dimple cytosis
36
Syndrome associated with thymic hypoplasia T cell or the T lymphocytes
DiGeorge syndrome
37
DiGeorge syndrome is associated with microdeletion in chromosome band?
22q11.2
38
Significant preference for the helper or inducer subset of lymphocytes
HIV or aids
39
Retroviral infection characterized by progressive dysfunction of helper T cell
HIV
40
Symptoms of late phase of HIV 1 infection
 Weight loss, fever multiple secondary infections
41
Hallmark of AIDS
Pneumocystis carinii
42
Most frequent malignancy observed in aid in invasive variant of
Kaposi sarcoma
43
Lymphocyte disorder that presents butterfly rash
Systemic lupus erythematosus
44
Classic but outdated test for SLE
LE cell
45
Drugs can produce an SLE syndrome
Hydralazine procainamide isoniazid
46
47
 term used for decreased leukocyte count
Leukopenia
48
Term used for increase leukocytes
Leukocytosis
49
Inflammatory condition caused by heat and cold surgery and stressful activities
Neutrophilia
50
Condition observe in active allergic disorders and asthma and hay fever
eosinophilia
51
Crystal structure seen in eosinophilic inflammation
 charcoal, Leyden crystals
52
Not affected by factors such as time of day, age and physical activity
Basophilia 0.075×10^9/L
53
Inability to release mature granulocytic into blood
Myelokathexis
54
Stress related condition related to action of glucocorticosteroid hormone
Eosinopenia
55
Occur in the time of ovulation
Basopenia
56
Condition which prominent dark granulation, observes in neutrophils and RNA
Toxic granulation
57
Single or multiple light blue staining inclusions on wright stain blood smears also seen in May-Hegglin anomaly
Dohle bodies
58
associated with vitamin B 12 or folic acid deficiency exist as oval shaped erythrocytes
Hyper segmentation
59
Disorder caused by B-glucocerebrosidase cerebral, resulting in accumulation of glucocerebroside
Gaucher disease
60
Condition associated with deficiency of sphingomyelin, and accumulation of sphingomyelin
Niemann pick disease
61
Benign hereditary disorder, involving absence of myelomaperoxides enzyme in neutrophils and monocytes
Myeloperoxidase deficiency
62
Screening test used to evaluate neutrophil in chronic granulomatous
Nitro blue tetrazolium
63
Neutrophil can ingest but not kill catalase positive
Chronic granulomatous disease
64
Disorder marked by inability of parasite to produce oxygen species
Chronic granulomatous disease
65
Most serious disorder related to the fact in microbial activity
Chronic granulomatous disease
66
Vacuole bound, colonies, known as morulae
Erlichia
67
Purple red granules, composed of mucopolyssacharide
Alder reily inclusions
68
hereditary disease with gigantic and peroxides positive
Chediak Higashi syndrome
69
Poor granulated platelets and manifested abnormal bleeding tendencies
may hegglin anomaly
70
Hereditary anomaly, characterized by hypo segmentation of neutrophil, resemble eyeglasses
Pelger huert anomaly

HEMA 311 (12 decks)

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