RBC ABNORMALITIES

Question 1

Normal amount of hemoglobin and it has central pallor of 1/3 diameter

Answer 1

NORMOCHROMIC CELL

Question 2

Larger and paler than normal and it is associated with Microcytosis

Answer 2

HYPOCHROMIC CELL

Question 3

Increased hemoglobin content and smaller than normal

Answer 3

HYPERCHROMIC CELL

Question 4

Pertains to multiple color and blue presence of RNA due to combination of affinity of hemoglobin to acid stain and affinity of RNA to basic dye

Answer 4

POLYCHROMATIPHILIA / POLYCHROMASIA / DIFFUSE BASOPHILIA

Question 5

Slighty Microcytic and it indicates Reticulocytes

Answer 5

POLYCHROMASIA

Question 6

Access diff. types of hemolytic anemia, recovery from blood loss and bone marrow disorders

Answer 6

POLYCHROMASIA GRADING

Question 7

Conditions where red cell appears PALE

Answer 7

HYPOCHROMASIA

Question 8

2 possible causes of HYPOCHROMASIA

Answer 8

Decrease hemoglobin concentration

Abnormal thinness of cell (IDA & Thalassemia)

Question 9

Conditions where red cells are deeply stained to abnormal thickness of cell

Answer 9

HYPERCHROMASIA

Question 10

Red cell vary in size, both macrocytes and microcytes

Answer 10

ANISOCYTOSIS

Question 11

It has 6-8 um size and associated with acute post hemolytic anemia and PANCYTOPENIA, hallmark of aplastic anemia

Answer 11

NORMOCYTE

Question 12

Larger and greater than 8um

Answer 12

MACROCYTE

Question 13

Samller and less than 6um

Microcytosis is found in: IDA & Thalassemia

Answer 13

MICROCYTE

Question 14

Large oval shaped 9-12um

Megalocytosis is found in: Perniciuos anemia

Question 15

Red cell vary in shapes

Answer 15

POIKILOCYTOSIS

Question 16

Normal cell with biconcave dics shape and associated with acute post hemolytic anemia

Answer 16

DISCOCYTE

Question 17

Small dense RBC with few irreg spaced and lack of central pallor

Increase in sphingomyelin and Cholesterol

Associated with Neuroacanthocytosis, Severe liver disease, Hepatitis in Newborns, Malabsorption

Answer 17

ACANTHOCYTE / SPUR CELL

Question 18

Pocket book roll/ biscuit shape

Cell membrane is folded

Associated with HgSC ans HgCC

Answer 18

BISCUIT CELL / FOLDED RBC

Question 19

Resembles crenated RBC

Abnormal lipid content of membrane and change in omsotic pressure

Associated with Uremia, MAHA, Liver ds, DIC, TTP, HELLP, PKD

Answer 19

BURR CELL SEA URCHIN / ECHINOCYTE

Question 20

Cell with eccentric vacuoles

G6PD def resulting to accumulation of heinz bodies

Associated with G6PD def., HUS, MAHA

Answer 20

BLISTER CELL / BITE CELL

Question 21

ATP deficiency due to prolonged storage of anticoagulayed blood

Associated with artifactual

Answer 21

ECHINOCYTE / CRENATED CELL (SEA URCHIN)

Question 22

Bull’s eye appearance amd colorless area and peripheral ring

Deficiency in cholesterol and lecithin

Associated with thalassemia, liver ds, HA,HbSC, HbCC, LCAT deficiency., Obstructive liver

Answer 22

CODOCYTES / TARGET CELL / MEXICAN HAT CELL

Question 23

Teardrop or pear with single short or long protrusion

Squeezing and fragmentation during Splenic Passage

Associated with HA,MA,MMM

Answer 23

TEARDROP CELL / DACRYOCYTES

Question 24

Normal central pallor (Pencil or Sausage)

It has shortened life span

Defective spectrin and band protein 4.1

Associated with MA, Hypochromic anemia, Hereditary ovalocytosis

Answer 24

ELLIPTOCYTES / OVALOCYTES

Question 25

Lacks of central pallor Spectrin deficiency and interaction of spectrin with other skeletal protein Associated with Chronic lymphocytic, leukemia, Immune hemolytic anemia due to ABO

Answer 25

SPHEROCYTE / BALL SHAPE

Question 26

Thin and elongated with pointed ends

Answer 26

SICKLE CELLS / DREPANOCYTES

Question 27

Contracted and fragmented cell Cell fragmentation due to trauma Associated with MAHA, TTP, DIC, HUS, uremia

Answer 27

SCHIZOCYTE

Question 28

Sit-like area of central pallor

Answer 28

STOMATOCYTE / MOUTH CELLS

Question 29

What inclusion body has Dark blue and bluish tinge

Answer 29

DIFFUSE BASOPHILIA

Question 30

What inclusion body has dark blue purple and associated with LEAD POISONING

Answer 30

BASOPHILIC STIPPLING

Question 31

What inclusion body is not visible in wright stain and associated with G6PD def.

Answer 31

HEINZ BODY

Question 32

What inclusion body is irreg clusters of small and stain used is PERL’S PRUSSIAN BLUE

Answer 32

PAPPENHEIMER BODIES

Question 33

What inclusion body has rings or figure of 8 and remnant of mitotic spindle

Answer 33

CABOT RING

Question 34

What other inclusion body is not visible in wright stain

Answer 34

HgB H INCLUSIONS / GOLF BALL-LIKE

Question 35

Stacks of coins

Answer 35

ROULEAUX FORMATION