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Flashcards in Anti-infectives Deck (26):
0

Act on bowel wall and liver

Tissue amebicide

1

Act on bowel lumen

Luminal amebicide

2

Luminal amebicides

Diloxanide Furoate, Iodoquinol, Paramomycin

3

Tissue amebicide

Emetine, Metronidazole, Nitazoxanide

4

Asymptomatic E. histolytica cyst DOC

Diloxanide furoate

5

Mild to moderate intestinal infection DOC

Metronidazole + Luminal amebicide

6

Severe and Extraintestinal infection, Hepatic abscess DOC

Metronidazole/Imidazole + Luminal amebicide

7

Severe intestinal and extraintestinal amebiasis back up drug for Metronidazole

Emetine

8

Antiprotozoal that causes thyroid enlargement

Iodoquinol

9

Antiprotozoal that blocks ribosomal movement along mRNA

Emetine

10

Metallic tasting antiprotozoal

Metronidazole

11

Paramomycin MOA

Binds to 16s ribosomal subunit inhibiting protein synthesis

12

Cryptosporidiosis drug of choice

Nitazoxanide

13

Metronidazole-resistant amebiasis

Nitazoxanide

14

Pneumocystosis DOC for treatment and prophylaxis

Cotrimoxazole

15

Toxoplasmosis DOC for treatment and prophylaxis

Pyrimenthamine-Sulfadiazine

16

Cerebral toxoplasmosis on CT

Ring like opacities

17

Advanced East African sleeping sickness DOC

Suramine + Melarsoprol

18

Advanced West African sleeping sickness DOC

Pentamidine + Enflornithine

19

Anti-trypanosomal drug crossing the blood brain barrier

Melarsoprol and Enflornithine

20

Hemolymphatic stage, East african sleeping sickness DOC

Suramin

21

Hemolymphatic stage, West african sleeping sickness DOC

Pentamidine

22

Chagas disease DOC

Nifurtimox

23

Melarsoprol route of administration

Intramuscular

24

Leishmaniasis DOC (except India)

Sodium Stibogluconate

25

Leishmaniasis DOC in India

Amohotericin B / Miltefosine