Anti-Seizure Flashcards Preview

Pharmacology > Anti-Seizure > Flashcards

Flashcards in Anti-Seizure Deck (37):
0

Complex partial seizure / Simple partial seizure:
Loss of consciousness

Complex partial seizure

1

Complex partial seizure / Simple partial seizure:
Intact consciousness

Simple partial seizure

2

Phenytoin MOA

Na channel blocked

3

Carbamazepine MOA

Na channel blocked
Glutamate decrease

4

Valproic Acid MOA

Na channel blocked
Ca channel blocked
GABA decrease
NMDA blocked

5

Class of Phenytoin

Hydantoin

6

Teratogenic effect of phenytoin

Fetal hydantoin syndrome

7

Phenobarbital MOA

Na channel blocked
Glutamate decrease
GABA decrease

8

Class of carbamazepine

TCA

9

Teratogenic effect of Valproic acid

Spina bifida

10

Antiseizure drug for children and pregnant

Phenobarbital

11

Absence seizures DOC

Ethosuxamide

12

Ethosuxamide MOA

Ca channel blocked (t-type, thalamus)

13

Status Epilepticus DOC with no co-morbids

Diazepam

14

Clonazepam MOA

GABA decrease

15

Gabapentin MOA

Ca channel blocked
GABA decrease
Glutamate decrease

16

Lamotrigine MOA

Na channel blocked
Ca channel blocked
Glutamate channel blocked

17

Anti-seizure that cause Steven-Johnson syndrome

Lamotrigine

18

Ethosuxamide class

Cyclic ureide

19

Gabapentin class

GABA derivative

20

Lamotrigine class

Phenyltriazine

21

Levetiracetam class

Piracetam

22

Levetiracetam MOA

Ca channel blocked
GABA decrease
Glutamate decrease
Binds synaptic vesicular protein SV2A

23

Juvenile myocolonic epilepsy

Levetiracetam

24

Contraindication in Levetiracetam

Schizophrenia

25

Topiramate class

Monosaccharide derivative

26

Topiramate MOA

Na channel blocked
Ca channel blocked
GABA decrease
Glutamate decrease
Carbonic Anhydrase decrease

27

Anti-seizure with side effect of Lennox-Gastaut syndrome & West syndrome

Topiramate

28

Anti-seizure with most number of MOA

Topiramate

29

Bipolar Disorder (mania) DOC

Valproic Acid

30

Trigeminal Neuralgia DOC

Carbamazepine

31

Neuropathic pain DOC

Gabapentin
Pregabalin

32

Migraine DOC

Gabapentin
Phenytoin
Topiramate

33

Myoclonic and Atypical Absence DOC

Valproic Acid

34

Generalized Tonic-Clonic Seizure DOC

Phenytoin
Valproic acid
Carbamazepine

35

Partial seizure DOC

Phenytoin
Lamotrigine
Carbamazepine

36

Status Epilepticus DOC in hepatic failure

Lorazepam