Antidepressants & ECT I Flashcards
Decreased levels of what are found in patients who are prone to impulsive, violent suicidal acts?
CSF 5 HIAA
What chromosome is serotonin transporter gene (SERT) found on?
What functional polymorphism is found in promoter region of SERT gene? What condition results from people with the ss genotype?
44 base pair insertion (long - l) or deletion (short -s)
Depression or suicidal depression
Depletion of what amino acid can transiently reverse antidepressant response and cause short lived return of depressive symptoms?
What part of the brain is densely innervated by both noradrenergic and dopamine systems?
What neurotransmitter is involved in process of working memory to regulate behavior and attention?
What neurotransmitter is involved in acquisition of emotionally arousing memories?
What neurotransmitter modulates amygdala in such a way as to strengthen memory consolidation and fear conditioning?
What types of dopamine receptors are more likely to be found in limbic areas?
D3 and D4
What types of dopamine receptors are found more widely in brain and are predominant subtype in striatum?
D1 and D2
Related to motor function
Related to reward and motivation
Related to memory and attention
Related to reinforcing properties of variety of drugs of abuse and pleasurable activities
Mesolimbic to nucleus accumbens
What neurotransmitter has a role in promoting interest and motivation?