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Flashcards in Antidotes Deck (34):
1

drugs that can be used to reverse neuromuscular blockade

Cholinesterase inhibitors
- Neostigmine

2

Drugs that can reverse Digoxin/ cardiac glycosides intoxication?

Digoxin immune FAB

3

Opioid overdose
(Morphine, heroine, methadone)

Naloxone, Naltrexon

4

Benzodiazepine overdose?

Flumazenil -- fyi: can precipitate seizures

5

Phencyclidine (PCP) overdose

Benzodiazepines, rapid-acting antipsychotic (Haloperidol)

6

TCA overdose

NaHCO3 (Sodium Bicarb) because TCA are weak acid

7

Iron

deferoxamine

8

Lead

EDTA, succimer, or dimercaprol

9

Cyanide

nitrites, hydroxocobalamin, thiosulfate

10

methhemoglobin

Methylene blue, Vitamin C

11

Carbon monoxide

100% O2 and hyperbaric Acid

12

methanol or ethylene glycol

Fomepizole -- inhibits alcohol dehydrogenase
Ethanol
Hemodialysis

13

Benzodiazepine overdose

Flumazenil

14

Heparin

Protamine Sulfate

15

Warfin

Vit K, Fresh Frozen Plasma (FFP)

16

Thromboyltics overdose

Aminocaproic acid

17

Myelosuppression caused by Methotrexate

Leucovorin

18

5- Fluorouracil toxicity

Uridine

19

hemorrhagic cystitis due to Cyclophosphamide

give mesna

20

used to prevent cardiotoxicity of doxorubicin and daunorubicin

Dexrazoxane

21

nephrotoxicity of Cisplatin, Carboplatin, or oxaliplatin

amifostine (free radical scavanger)

22

Acetaminophen

N-acetylcysteine (replenish glutathione)

23

AChE inhibitors, organophosphates

Atropine > pralidoxime

24

Amphetamines

NH4Cl (acidify urine) basic

25

Antimuscarinic, anticholinergic agents

Physostigmine salicylate, control hyperthermia

26

Beta blockers

Glucagon

27

Carbon monoxide

100% oxygen

28

Copper, arsenic, gold

Penicillamine

29

Cyanide

Nitrate + Thiosulfate
hydroxocobalamin

30

Digitalis (digoxin)

Anti-dig Fab fragments

31

Mercury, arsenic, gold

Dimercaprol (BAL)
Succimer

32

Salicylates

NaHCO3- (alkalizes urine)
Dialysis

33

tPA, streptokinase, urokinase

Aminocaproic acid

34

Methamphetamine overdose

ammonium chloride -- helps clear the drug