Different DNA and RNA polymerases Flashcards Preview

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Flashcards in Different DNA and RNA polymerases Deck (12):
1

DNA III polymerase

prokaryotes

Leading and lagging strands
Has 5'-->3' synthesis and
3'-->5"exonuclease activity

2

DNA I polymerase

Prokaryotes

Excises RNA primer
-5' --> 3' exonuclease activity along with 5'-->3' DNA synthesis and proof reading 3'--> 5'

3

DNA polymerase alpha

Eukaryotes

RNA primer and builds okazaki fragments on lagging strand

4

DNA polymerase beta

Eukaryotes

DNA repair

5

DNA polymerase Gamma

Eukaryote

LEADING STRAND

6

DNA polymerase gamma

mitochondrial DNA

7

RNA polymerase I

rRNA

is synthesized in nucleolus

8

RNA polymerase II

mRNA

9

RNA Polymerase III

tRNA

10

alpha- amanitin

Found in Amanita Phalloides (death cap mushrooms) and it inhibits RNA polymerase II. Can cause severe hepatotoxicity if ingested

11

Rifampin

inhibits RNA polymerase in prokaryotes

(recall that prokaryotes have only one type of RNA polymerase and it is a multisubunit complex that makes all 3 kinds of RNA)

12

Actinomycin D

inhibits RNA polymerase in both prokaryotes and eukaryotes