Antimycobacterial Drugs Flashcards Preview

Pharmacology 1 > Antimycobacterial Drugs > Flashcards

Flashcards in Antimycobacterial Drugs Deck (10):
0

TB meds
MOA: inhibit mycolic acid synthesis
SE: neurotoxicity & hepatitis, drug induce lupus

Isoniazid

1

DOC: drug induced (isoniazid) neurotoxicity

Pyridoxine

2

MOA: inhibits DNA dependent - RNA polymerase

Rifampicin

3

SE: red orange urine, flu likesymptoms

Rifampicin

4

MOA: inhibits RNA-dependent DNA polymerase

Antiretrovirals

5

MOA: inhibits arabinosyl transferases involve in the synthesis of arabinogalactan
Bacteriostatic

Ethambutol

6

SE: visual disturbance ( red-green color blindness)

Ethambutol

7

SE: most hepatotoxic anti tb med
Hyperuricemia

Sterilizing agent

Pyrizinamide

8

DOC: leprosy

Dapsone - inhibits folic acid synthesis
Used in combination with rifampicin & clofazimine

9

Drugs for Atypical mycobacteria

Prophylaxis- clarithromycin or azithromycin with/ without rifabutin in px with CD4 counts less than 50/L

Tx- Azithromycin or clarithromycin w/ ethambutol & rifabutin