Toxicities and Antidotes Flashcards Preview

Pharmacology 1 > Toxicities and Antidotes > Flashcards

Flashcards in Toxicities and Antidotes Deck (35):
1

Digitalis toxicity

Lidocaine (class IB)
Digoxin antibodies

2

Acetaminophen overdose

Acetylcysteine

3

Cholinesterase inhibitors

Atropine + Pralidoxime

4

Quinidine, TCAs

Bicarbonate

5

Fluoride, CCBs

Calcium

6

Iron toxicity

Deferoxamine

7

Caffeine, theophylline, sympathomimetics

Esmolol

8

Methanol, ethylene glycol

Ethanol
Fomepizole (Ethanol dehydrogenase antagonist)

9

Benzodiazepines, Zolpidem

Flumazenil

10

Beta adrenoreceptor blockers

Glucagon

11

Hypoglycemics

Glucose

12

Cyanide poisoining

Hydroxocobalamine
inhaled amyl nitrite + IV sodium nitrite + IV sodium thiosulfate

13

Opioid analgesics

Naloxone

14

Carbon monoxide

Hyperbaric Oxygen

15

Muscarinic reeptor blockers

Physostigmine

16

Organophosphates

Pralidoxime

17

Heparin

Protamine sulfate

18

Warfarin

Vit K, FFP

19

Inorganic lead poisoning

Chelation - oral succimer (OPD);
EDTA +/- Dimercaprol severe cases

20

Organic lead poisoning

decontamination, seizure control

21

Arsenic poisoning

Chelation w/ Dimercaprol

22

Mercury poisoning

oral Succimer or IM Dimercaprol

23

Copper toxicity

Penicillamine

24

Methotrexate toxicity

Leucoverin

25

Cyclophosphamide toxicity

MESNA (mercaptoethane sulfate)

26

Doxorubicin toxicity

Dexrazoxane

27

Cisplatin toxicity

Amifostine

28

Methemoglobinemia

Methylene blue

29

Cardiotoxicity from Bupivacaine/ Ropivacaine

Intralipid (fat emulsion used in TPN)

30

Lithium toxicity

Hemodialysis

31

Clonidine induced rebound tenderness

Phentolamine

32

Class IA antiarrythmics drug overdose
(Procainamide, Quinidine, Disopyramide)
drug induce arrythmias

Sodium lactate

33

heparin induced thrombocytopenia

lepirudin

34

Heparin induced bleeding

Protamine sulfate

35

Antidote for thrombolytic overdose

Aminocaproic adic/ Tranexamic acid