Toxicities and Antidotes

Question 1

Digitalis toxicity

Answer 1

Lidocaine (class IB)
Digoxin antibodies

Question 2

Acetaminophen overdose

Answer 2

Acetylcysteine

Question 3

Cholinesterase inhibitors

Answer 3

Atropine + Pralidoxime

Question 4

Quinidine, TCAs

Answer 4

Bicarbonate

Question 5

Fluoride, CCBs

Answer 5

Calcium

Question 6

Iron toxicity

Answer 6

Deferoxamine

Question 7

Caffeine, theophylline, sympathomimetics

Answer 7

Esmolol

Question 8

Methanol, ethylene glycol

Answer 8

Ethanol

Fomepizole (Ethanol dehydrogenase antagonist)

Question 9

Benzodiazepines, Zolpidem

Answer 9

Flumazenil

Question 10

Beta adrenoreceptor blockers

Answer 10

Glucagon

Question 11

Hypoglycemics

Answer 11

Glucose

Question 12

Cyanide poisoining

Answer 12

Hydroxocobalamine

inhaled amyl nitrite + IV sodium nitrite + IV sodium thiosulfate

Question 13

Opioid analgesics

Answer 13

Naloxone

Question 14

Carbon monoxide

Answer 14

Hyperbaric Oxygen

Question 15

Muscarinic reeptor blockers

Answer 15

Physostigmine

Question 16

Organophosphates

Answer 16

Pralidoxime

Question 17

Heparin

Answer 17

Protamine sulfate

Question 18

Warfarin

Answer 18

Vit K, FFP

Question 19

Inorganic lead poisoning

Answer 19

Chelation - oral succimer (OPD);

EDTA +/- Dimercaprol severe cases

Question 20

Organic lead poisoning

Answer 20

decontamination, seizure control

Question 21

Arsenic poisoning

Answer 21

Chelation w/ Dimercaprol

Question 22

Mercury poisoning

Answer 22

oral Succimer or IM Dimercaprol

Question 23

Copper toxicity

Answer 23

Penicillamine

Question 24

Methotrexate toxicity

Answer 24

Leucoverin

Question 25

Cyclophosphamide toxicity

Answer 25

MESNA (mercaptoethane sulfate)

Question 26

Doxorubicin toxicity

Answer 26

Dexrazoxane

Question 27

Cisplatin toxicity

Answer 27

Amifostine

Question 28

Methemoglobinemia

Answer 28

Methylene blue

Question 29

Cardiotoxicity from Bupivacaine/ Ropivacaine

Answer 29

Intralipid (fat emulsion used in TPN)

Question 30

Lithium toxicity

Answer 30

Hemodialysis

Question 31

Clonidine induced rebound tenderness

Answer 31

Phentolamine

Question 32

Class IA antiarrythmics drug overdose (Procainamide, Quinidine, Disopyramide) drug induce arrythmias

Answer 32

Sodium lactate

Question 33

heparin induced thrombocytopenia

Answer 33

lepirudin

Question 34

Heparin induced bleeding

Answer 34

Protamine sulfate

Question 35

Antidote for thrombolytic overdose

Answer 35

Aminocaproic adic/ Tranexamic acid