Antiprotozoal drugs Flashcards Preview

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Flashcards in Antiprotozoal drugs Deck (16):
0

Tissue schizonticide

Primaquine

1

Blood schizonticides

Chloroquine
Quinine

2

Gametocides

Primaquine

3

Sporonticides

Proguanil
Pyrimethamine

4

Class: antimalarial dmards
MOA: prevents polymerization of heme into hemozoin
Use: malaria (nonfalciparum)
Chemoprophylaxis

Chloroquine

5

Chloroquine SE:

Auditory impairment, retinal damage, psychosis

6

Use: severe falciparum malaria
SE: cinchonism

Quinidine

7

DOC for malaria in pregnant patients

Quinine

8

Headache, tinnitus, vertigo

Cinchonism

9

Complication or P.falciparum
Characterized by intravascular hemolysis, massive hemoglobinuria and acute renal failure

Black water fever
Tx quinine

10

MOA: forms electron transferring redox compounds that act as cellular oxidants
Uses: radical curer of P.Vivax, P.Ovale

Primaquine

11

Used for multidrug resistant malaria

Doxycycline

12

DOC of uncomplicated falciparum malaria in the philippines

Artemether-lumefantrine (Co-artem)

13

Chemoprophylaxis
Chloroquine sensitive area

Chloroquine 500 mg/tab 1 tab weekly

14

Chemoprophylaxis
Chloroquine resistant areas

Mefloquine 250 mg/tab 1 tab weekly
Malarone (atovaquone 250 mg/ proguanik 100 mg/ tab 1 tab daily

15

Chemoprophylaxis for multidrug resistant malaria

Doxycycline 100 mg/tab 1 tab daily