Antipsychotics Flashcards Preview

Boards > Antipsychotics > Flashcards

Flashcards in Antipsychotics Deck (13):
1

What are the low-potency typical antipsychotics?

Chlorpromazine
Thioridazine

2

What is the side effect seen with chlorpromazine or thioridazine?

Anticholinergic effects

3

What is the major action of low-potency typical antipsychotics? What other receptors does it block?

Blocks D2

Blocks muscarinic, alpha1, and H1 receptors

4

What are the high-potency typical antipsychotics?

Haloperidol
Fluphenazine
Loxapine
Thithixene
Trifluroperazine

5

What side effects are often seen with high-potency typical antipsychotics?

Extrapyramidal symptoms
Neuroleptic Malignant Syndrome (NMS)
Tardive dyskinesia (seen with longterm use)

Fewer anticholinergic side effects

6

What are the symptoms of NMS?

Delirium
Autonomic instability
Muscle rigidity
Myoglobinuria
Hyperpyrexia

7

How is NMS treated?

Dantrolene
Bromocriptine

8

What are the benefits of using atypical antipsychotics?

Fewer EPS or anticholinergic side effects
Have more of an effect on negative symptoms than typicals do

9

What side effect is seen with atypical antipsychotics that isn't seen with typicals?

Weight gain

10

What are the primary sites of action of atypicals? What other receptors are blocked?

Block dopamine and serotonin receptors

Also block alpha and H receptors

11

What are the atypical antipsychotics?

Qlanzepine
Quetiapine
Risperidone
Aripiprazole
Clozapine

12

What is the most potent of the atypicals?

Clozapine

13

Is clozapine commonly used?

No. Clozapine causes agranulocytosis