Arterial Physiology and Hemodynamics Flashcards

1
Q

Cardiac contraction begins:

A

Pressure in the left ventricle rises rapidly.
Left ventricle pressure exceeds that in the aorta.
aortic valve opens, blood is ejected, BP rises

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2
Q

The heart pump:

A

Generates the pressure to move the blood.
Results in a pressure wave that travels rapidly throughout the system, demonstrating a gradual transformation as it travels distally.

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3
Q

Each beat pumps about how many milliliters of blood into the aorta causing a blood pressure pulse?

A

70

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4
Q

What governs the amount of blood that enters the arterial system?

A

Cardiac output

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5
Q

What determines the amount of blood that leaves the arterial system?

A

arterial pressure and total peripheral resistance

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6
Q

movement of any fluid medium between two points requires what two things?

A

A pathway along which the fluid can flow.

Difference in energy levels (pressure difference)

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7
Q

The amount of flow depends upon what?

A

Energy difference.

Any resistance which tends to oppose such movement.

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8
Q

Flow depends upon resistance and flow rate:
lower resistance=
higher resistance=

A

higher flow rate

lower flow rate

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9
Q

Total energy contained in moving fluid is the sum of what energies?

A

pressure, kinetic, and gravitational

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10
Q

What is the major form of energy for circulating blood?

A

pressure energy (mmHg)

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11
Q

What energy is small for circulating blood? Expressed in terms of fluid density and its velocity measurements.

A

kinetic energy

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12
Q

What is equivalent to the weight of the column of blood extending from the heart to level where pressure is measured?

A

gravitational energy or hydrostatic pressure

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13
Q

When supine there is 0 mmHg against the arterires and veins at the ankle. When standing the HP increases to what?

A

100 mmHg

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14
Q

An energy gradient is needed for what?

A

moving blood from one point to another. greater the gradient, the greater the flow.

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15
Q

R= 8nL/πr^4

A
R= resistance
n= viscosity
r= radius
L= vessel length
R is directly proportional to variables in numerator and indirectly to the variable in the denominator.
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16
Q

What has a more dramatic effect on resistance than viscosity and vessel length?

A

vessel diameter

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17
Q

factors affecting resistance to flow?

A

physical properties of the fluid and what its moving through

18
Q

viscosity ans velocity
greater viscosity=
less viscosity=

A

less velocity

greater velocity

19
Q

viscous energy loss is due to what?

A

increased friction between molecules and layers

20
Q

Inertial losses occur with deviations from laminar flow due to what?

A

Changes in direction and/or velocity. occurs at the exit of a stenosis

21
Q

Poiseuilles equation helps answer the question of how much fluid moves through vessel and defines the relationship between what?

A

Pressure, volume flow, and resistance

Q=P/R

22
Q

area and velocity
greater area=
less area=

A

less velocity

greater velocity

23
Q

pressure/velocity relationships

A

sum of pressure, kinetic, and gravitational energies. If one changes the others make up for the difference in order to maintain the original total fluid energy.

24
Q

velocity and pressure
greater velocity=
less velocity=

A

less pressure

greater pressure

25
Q

Systole:
Late systole/early diastole:
Late diastole:

A

Forward flow
Temporary flow reversal
Forward flow again

26
Q

low resistance flow consists with what? continuous

A

ICA, vertebral, renal, celiac, splenic, hepatic

27
Q

high resistance flow occurs in what? pulsatile

A

ECA, subclavian, aorta, iliac, extremity arteries, fasting SMA

28
Q

Doppler flow distal to a significant stenosis is?

A

lower resistance, more rounded, and weaker in strength

29
Q

Doppler flow prox to stenosis is what?

A

Higher resistance

A normally high resistant signal may become monophasic closer to stenosis.

30
Q

Pulsatile changes in medium/small sized arteries of the limbs are increased. Pulsatility changes usually decreased in the minute arteries.

A

vasoconstriction

31
Q

decreased pulsatile changes in medium/small arteries of the limbs. Pulsatility changes are increased in minute arteries.

A

vasodilatation

32
Q

As the inflow pressure falls as a result of stenosis, the natural responsein periphery is to what?

A

Vasodialte to maintain flow

33
Q

collateral effects

A
Increased flow volume
Reversed flow direction
Increased velocity
Waveform pulsatility changes
Location of collaterals helps provide tentative area of obstruction
34
Q

Exercise should induce peripheral ______ which lowers distal peripheral ______, increasing blood flow.

A

vasodilatation, resistance

35
Q

What is the best single vasodilator of resistance vessels within skeletal muscles?

A

exercise

36
Q

What is the ability of most vascular beds to maintain constant level of blood flow over a wide range of perfusion pressures.

A

Autoregulation

37
Q

BP rise:

BP fall:

A

Constriction of resistance vessels.

Dilatation of resistance vessels.

38
Q

vasodilatation
vasoconstriction
what type of signals?

A

continuous, lower

pulsatile, higher

39
Q

Entrance into stenosis increase in doppler shift frequencies resulting in what?

A

spectral broading and elevated velocities

40
Q

post-stenotic turbulence

A

Flow quality is comprised of multiple changes in direction and spectral broadening as displayed by the spectral pattern.
Energy expended as heat.