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Bacteriology Pasteruellaceae Flashcards

(49 cards)

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1
Q

What are the virulence factors that allow for Pasterurellaceae can cause disease?

A

attachment by fimbriae or adhesions
avoidance of phagocytosis with capsules
cellular toxicity with exotoxins
local and systemic effects with endotoxins

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2
Q

Which gram negative bacteria do endotoxins play a greater role in?

A

enterobacterales

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3
Q

What are three negative effects exotoxins can have on a cell?

A

role in atrophic rhinitis
cause lung damage in pneumonia
toxic for phagocytic cells

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4
Q

Being that pasteruellacaea are present as normal flora how is it able to cause disease?

A

opportunistic infections

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5
Q

What host environmental factors contribute to disease development?

A

close quarters
poor ventilation
respiratory virus
young age
poor weather

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6
Q

Explain the pathogenesis of Pasteurellaceae infections

A

NF in respiratory tract
Insult (virus or stress)
bacteria get down into lungs
cause pneumonia

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7
Q

What can occur if different strains of Pasteurellaceae are around?

A

being that they are not part of the NF, they are in carrier animals and are considered to be “better pathogens”

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8
Q

What are some examples of different strains of Pasterurellacae?

A

P multocida capsule type A
P multocida capsule types B and E

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9
Q

Which animal species does P. multocida affect majorly?

A

production animals and companion animals

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10
Q

What are the.4 basic categories of disease associated with Pasturella?

A

pneumonia
rhinitis
bite wounds
septicemia

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11
Q

What is the most important disease caused by Pasteurella?

A

pneumonia

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12
Q

What disease complex is associated with Pasteruella multocida?

A

Bovine Respiratory Disease Complex or Shipping Fever

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13
Q

What does Shipping Fever cause?

A

severe, fibrinous, hemorrhagic, lobar pneumonia causing fibrinopurulent exudate in airways

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14
Q

What is a main factor that causes pneumonia from P. multocida?

A

transportation

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15
Q

What disease does P. multocida cause in rabbits?

A

Rhinitis - snuffles

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16
Q

What does snuffles cause from P. multocida?

A

mucopurulent with fever, nasal discharge, and respiratory distress can develop, septicemia

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17
Q

What is a common disease in pigs caused by P. multocida?

A

Atrophic Rhinitis in young pigs

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18
Q

Atrophic Rhinitis is a combined effect of what two bacteria?

A

Bordetella bronchiseptica allowing P. multocida type D to cause damage

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19
Q

What does B. bronchiseptica cause?

A

initial damage to nasal mucosa allowing P multocida to invade

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20
Q

How is P. multocida type D able to cause Atrophic rhinitis?

Study These Flashcards
A

have a dermonecrotic toxin that causes bone resorption of bony turbinates and suppresses osteoid synthesis adjacent to inflamed area

21
Q

What will you see clinically with Atrophic rrhintis?

Study These Flashcards
A

sneezing
epistaxis
facial distortion

22
Q

How are bite wounds able to cause disease with P.multocida?

Study These Flashcards
A

oral flora which have mixed infections are infected with a cat or dog bite

23
Q

What species can P. multocida cause septicemia in?

24
Q

Are strains of P. multocida that cause septicemia associated with normal flora?

25
What 3 diseases does Mannheimia haemolytica cause and in which species ?
Pneumonia/bronchopneumonia - Shipping Fever in cattle or enzootic pneumonia in sheep and goats necrotizing mastitis - ewes septicemia - lambs
26
What species is Actinobacillus equuli predominant in?
horses
27
What 3 diseases does Actinobacillus equui cause?
sleepy foal dx - septicemia in neonatal foals peritonitis in adult horses pneumonia and pleuropneumonia
28
What disease does Actinobacillus lignieresii cause?
wooden tongue in ruminants and is a result of trauma to oral cavity will see multiple pyogranulomatous abscesses
29
What species is A. pleuropneumoniae predominant in? What are the predisposing factors and what does it cause?
PIGS predisposing factors are crowding, poor ventilation, other infectious agents causes severe fibrinous pneumonia and pleuritis
30
What is Actinobacillus suis?
sepitcemia in pigs 1-8 weeks old
31
What is Glaeserella Parasuis? What species does it effect?What are the two diseases associated with it?
PIGS Bronchosepticemia Glasser's disease which causes septicemia and polyserositis which can be caused by stress
32
How does Histophilus somni cause disease and which species is it predominately seen in?
cows invades and disseminates via the bloodstream and produces disease where it localizes causing thrombotic lesions due to exotoxin
33
What three diseases can Histophilus somni cause?
Respiratory disease Thrombotic meningoencephalitis reproductive failure
34
What disease does Avibacterium paragallinarum cause and in which species?
disease in chickens causing inflammation of turbinates, sinus epithelium,, sometimes air sacculitis causes sneezing and facial swelling
35
How is Pasteruellacaeae grouped?
family
36
What are the main hosts affected by P. multocida?
cattle, dogs, cats, horses, pigs, sheep, goats, birds, rabbits, humans
37
What are the shared features associated with Pasteurellaceae?
gram negative short rods facultatively anaerobic (but like inc. CO2) oxidase positive non-motile grow on blood agar variable growth on MacConkey Agar
38
Which Pasterurellacae NOT grow on blood agar? What do these bacteria grow better on?
Histophilus, Glaaeserella, Avibacterium Chocolate agar
39
Which Pasteurellacae NOT grow on MacConkey?
multocida, Histophilus somni, Glaeserella parasuis
40
Compared to Enterobacterales, what diseases do Pasteurellacae cause?
Broader range
41
Which Pasteurellaceae cause more broad range of infectious disease?
Pasteruella, Mannheimia, Actinobacillus, Histophilus
42
Which Pasterurellacaea cause more specific syndromes?
Glaeserella and Avibacterium
43
Where do most Pasteurellaceae come from?
Normal flora of mucous membranes of animals and birds in the Upper respiratory tracts, digestive tracts, lower genital tract
44
Which Pasterurellaceae cause dx in the upper respiratory tract?
P. multifocida, M. haemolytica, Actinobacillus, G parasuis, H. somni
45
Which Pasteurellaceae cause dx in the digestive tract?
P. multocida, actinobacillus
46
Which Pasteurellaceae cause dx in the lower genital tract?
Actinobacillus suis and H somni
47
While most Pasteurellaceae are part of the normal flora in all animals, some are only present on _____?
carriers in upper resp. tract
48
Can Pasteurellaceae survive in the environment for a long time?
nope
49
How are Pasteurellaceae transmitted?
inhalation, direct inoculation

Dealing with Threats (27 decks)

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