biochem1

Question 1

inheritance of classic galactosemia

Answer 1

autosomal recessive

Question 2

inheritance of rett syndrome

Answer 2

x linked dominant disorder

Question 3

chromosomal posistion determined by

Answer 3

FISH

Question 4

a2delta 2

Answer 4

hba2

Question 5

cytochrome oxdiase

Answer 5

final component of etc and fucntions to convert molecular oxygen to water

Question 6

enzymes for PPP reside in the

Answer 6

cytosol

Question 7

counterregulatroy hormones

Answer 7

glucagon
epinepherine
cortisol and GH (alter trancirpitoin of many genes to conesrve glucose)

Question 8

REDUCING SUGARS

Answer 8

GLUCOSE
galactose f
fructose

Question 9

monocistrionic

Answer 9

eukaryotic

Question 10

lac operon regulated by 2 distinct mechanisms

Answer 10

negatively by binding of repressor protein to operator locus and positively by camp-cap binding upstrream from promoter region

Question 11

lac operon positively reguatled by cap to site slightly upstream from promoter region; only occurs when camp is

Answer 11

high. thus since glucose decreases activaty of adenyl cyclase (reducing intracellular camp), the lac operon is repressed in high glucose conditiosn

Question 12

4 cal per gram of

Answer 12

protein or cargb

9 cal per gram of ffat

Question 13

acute GI hemorrageh caues what tyep of loss of ecf volume

Answer 13

isotonic

Question 14

myoglobin has a much higher affinity of oxygen than hemoglboin

Answer 14

true

Question 15

lactose breaks into

Answer 15

galactose + glucsoe

maltose = 2 glucose

Question 16

in fructokinase defincieync, what takes over role of metabolizign fructose

Answer 16

hexokinase

(converts fructose to fructose 6 phosphate

Question 17

ristocetin cofactor assay measures in vitro vwf dependent platelet agglutination

ristocetin activates GP Ib receptors on platelts and makes them available for vwf binding; when

Answer 17

true

Question 18

when normal plasma that contains is added, why does appropatei platelet agglutinator occur

Answer 18

seen in vwf.

bc normal plasma contains vwf

Question 19

geneetic code is considered degenerate which means

Answer 19

more than 1 codon can code for a partiuclar amino acid

Question 20

why does excessive raw egg white consumption lead to biotin deficieicy

Answer 20

due to high levels of biotin binding avidin in egg white

Question 21

rubber like properties of elastin due to

Answer 21

high content of nonpolar amino acids and extenssive cross linking between elastin monomers faicliated by lysyl oxidase.

Question 22

induce posttranscirptional gene silencing by base pairing with complmementary sequences within target mrna molecules

Answer 22

short non coding rna sequences (micro rna and small intefering RNA)

Question 23

erythrocytes can bypass glycolytic pathway by

Answer 23

bisphosphoglycerate mutatse

converts 1,3bpg to 2,3 bpg in a step that produces no ATP

Question 24

cyandie inhibits

Answer 24

cytochrome c oxidase in mitochondria used as an ETC enzyme essential for ox phosphroylation

Question 25

homeobox genes encode

Answer 25

dna binding trasncirption factors that play an imortant role in segmental organization of embryo along cranio caudal axis

Question 26

ketone bodies cannot be used to synthesize

Answer 26

glucose

Question 27

reversibly binds hemogblion

Answer 27

CO

Question 28

red pulp in spleen removeal

Answer 28

damaged RBCs | unqdergo hyperplasia in pyruvate kinase deficiiency

Question 29

measure amount of protein in body fluids

Answer 29

ELISA

Question 30

progeny contains genetic material from both viruses

Answer 30

reassormtent | segmented viruses

Question 31

sickling occurs with high levels of

Answer 31

2, 3 bpg

Question 32

brown pigment gllstones formed by

Answer 32

composed of calciulm salts of ucb and arise secondary to bacterial or helminithic infection releaseBETA-GLUCURONIDASE ; hydrolyzes bilirubin glucuronides to ucb

Question 33

ammonia level in methylmalonic acdiemia

Answer 33

high | organic acids directly inhibt urea cycle leading to hyperammonenima