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Therapeutics III Test 3 > Bipolar 2 > Flashcards

Flashcards in Bipolar 2 Deck (18)
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1

what are 3 points about the desired outcomes of treating bipolar disorder

1. aim for recovery, not limited improvement
2. select drug regimens that are well tolerated
3. assess acute episodes vs. maintenance drug needs

2

what is the 'gold standard' for bipolar disorder treatment

lithium

3

what anticonvulsants can be used for treated bipolar disorder

1. valproic acid
2. lamotrigine
3. carbamazepine

4

is lithium indicated for acute or maintenance therapy of bipolar disorder

indicated for both

5

what is monotherapy of lithium not indicated for?

rapid cyclers or mixed states

6

when should labs be taken after initiating lithium

after 3-5 days (steady state is 5 days)

7

how is lithium metabolized/ excreted

renally, no hepatic metabolism

8

what pre-lithium work up is required

CBC
Urinalysis
Pregnancy test
Thyroid function test
Renal function
EKG
Electrolytes

9

why is CBC needed with pre lithium work up

can cause leukocytosis

10

what electrolyte imbalance is common with lithium

hyponatremia

11

what is the initial dosing range of lithium for bipolar disorder

600-900mg/day

12

If there is a need to raise lithium levels by 0.3 mEq/L, how much lithium should be given

300 mg

13

what are the therapeutic concentration levels of lithium for acute mania?

0.8-1.2

14

what are the therapeutic concentration levels of lithium for maintenance in treating bipolar disorder

0.6-1

15

when should labs be taken for a patient on lithium for most accurate levels?

12 hours after a dose

16

serum levels should be drawn how often for patients on lithium

weekly for 2 weeks; then every 3-6 months once stable

17

at what level does can lithium toxicity occur?

1.5 mEq/L or greater

18

what side effect is common with lithium

hand tremor (course hand tremor may be toxicity)