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Flashcards in headache 3 Deck (21)
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1

what is MIDAS

Migraine Disability Assessment Test - series of questions about headaches over the past 3 months

2

what is the predominate symptom of migraines

pain

3

what 6 types of drugs can be used to treat headaches

1. analgesics
2. NSAIDs
3. ergot alkaloids
4. serotonin agonists
5. opiate analgesics
6. antiemetics

4

True/ False
analgesics/ NSAIDs are site specific for migraine associated pain

false

5

what treatment corresponds with mild to moderate migraine disability

analgesics/ NSAIDs

6

what are the most commonly used NSAIDs for migraines

ibuprophen, naproxen, and aspirin

7

what are considered second line for migraines

1. Tylenol
2. butabital
3. caffeine
4. dichloalphenazone
5. isometheptene

8

why is butabital avoided for migraine treatment

causes rebound headaches and leads to overuse

9

what patients should use analgesics/ NSAIDs with caution?

1. ulcer disease
2. renal disease
3. cardiac disease
4. hypersensitivity

10

how do ergot alkaloids work for migraines

5HT1 agonists that constrict intracranial blood vessels and inhibit trigeminovascular system

11

what is the predominate pathophysiology for migraines

vasodilation

12

what treatment corresponds with moderate to severe migraines

ergot alkaloids

13

what are some of the ergot alkaloids used to treat migraines

ergotamine tartrate
dihydroergotamine

14

when should ergot alkaloids be used

early in the attack when the headache is first starting

15

why is ergotamine often combined with caffeine

1. enhances absorption
2. aids in analgesia

16

what is the daily dosing for ergotamine

rectal = 4 mg per day
oral = 6 mg per day

17

what is the weekly doising for ergotamine

10 mg per week for both oral and rectal

18

what type of ergot alkaloid is a potent arterial constrictor; having more systemic effects?

ergotamine

19

what ergot alkaloid has less systemic effects

dihydroergotamine

20

what ergot alkaloid does not appear to cause rebound headaches

dihydroergotamine

21

how is dihydroergotamine administered

nasal and parenteral