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Flashcards in sleep 1 Deck (17)
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1

what stage of sleep eats up 50% of time sleeping

stage 2

2

what stages of sleep are considered deep sleep

stage 3 and 4

3

what neurotransmittors cause sleepiness

GABA
Melatonin
Adenosine

4

all patients with insomnia should have what 3 types of 'treatment'

1. identifying the cause
2. patient education on sleep hygiene
3. stress management

5

what type of insomnia is characterized by an acute stressor, and good sleep hygiene

transient insomnia

6

what type of insomnia can last up to 3 weeks, usually due to stress

short term insomnia

7

what is common denominator treatment of all 3 types of insomnia

educate on good sleep hygeine

8

what is an ideal agent for insomnia do?

1. fast onset
2. maintain sleep
3. no hangover
4. no tolerance
5. no abuse potential

9

what are the 3 most common antihistamines used for sleep

1. diphenhydramine
2. doxylamine
3. pyrliamine

10

what are 2 contraindications for antihistamines

1. closed angle glaucoma
2. urinary obstruction

11

what antidepressants are most common for treating insomnia

1. amitriptyline
2. trazodone
3. mirtazepine

12

what is the precursor to serotonin and melatonin

L-tryptophan

13

what are the 4 most commonly used drugs for treating insomnia

1. traditional benzodiazepines
2. zolpidem
3. zaleplon
4. eszopiclone

14

why should benzodiazepines be avoided for insomnia

increase time in stage 2; but decrease stage 3, 4, and 5 (deep sleep and REM)

15

what benzodiazepine has a very short half life and is often used for insomnia

triazolam

16

what adverse effect is seen with all nonbenzo GABA agonists

amnesia

17

what drug works best for people needing help falling asleep but don't have problems staying asleep

zaleplon (sonata)