Bleeding in early pregnancy Flashcards

(37 cards)

1
Q

What is the most common reason for bleeding in early pregnancy

A

Spontaneous miscarriage

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2
Q

Define spontaneous miscarriage

A

Expulsion or removal of the products of conception prior to 24 weeks gestation

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3
Q

How common is a miscariage

A

10-15 percent of pregnancies

45-55 percent if using B-HCG

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4
Q

Name other reasons for bleeding in early pregnancy

A

ectopic pregnancy
Hydratiform mole
lower genital tract causes

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5
Q

What are the ‘types’ of miscarriage

A
Threatened
Inevitable
Incomplete
Complete
Septic
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6
Q

Define threatened

A
Not painful
Not profuse bleeding
Cervix closed
Uterus= gestational age
Fetal heart present
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7
Q

Define incomplete

A
Lower abdo pain
Heavy vaginal bleeding with clots
Shock +ve
Tenderness
Cervix open
Products of conception may be present in cervix
Fetal heart not present
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8
Q

define complete

A

Similar to incomplete history but followed by cessation of bleeding.
Uterus smaller than gestational age
Cervix closed
Fetal heart not present

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9
Q

define septic miscarriage

A

INfection following a miscarriage

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10
Q

define inevitable

A

similar to incomplete but not as far along in the process

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11
Q

What are the possible factors which can lead to a miscarriage

A

Abnormal conceptus - chromosomal abnormalities

Uterine abnormalities - bicornuate uterus, septae, marked ante/retrofexion, fibroids, incompetent cervix

Acquired disease - infection, malaria, influenza, hypertension, diabetes, thyroid

Toxins - durgs, smokig, alchohol, chemotherapy

Immunoogical - antiphospholipid syndrome, lupus

Endocrine- deficient cirpus luteum and progesterone

Trauma- amniocentesis, coitus, surgery

Foreign body - IUS/IUD

Psychological - stress/anxiety

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12
Q

What investigations should be done in a miscarriage

A
Hb
Blood group and Rh
group and save
Pregnancy test
Serium b-hcg - hydratiform mole
ECS and blood culture- sepsis
Ultrasound
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13
Q

How is a threatened miscarriage treated

A

Reassure and rest
Avoid coitus
Remove IUCD if present
Aspirin, heparin or prednisolone for APLS after 1st trimester

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14
Q

How is an inevitable miscarriage treated

A

Allow uterus to evacuate itself
Pain relief
Oxytoxic
Evacuation of uterus if needed

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15
Q

How is an incomplete miscarriage treated

A
Blood transfusion if shocked
Oxytoxic
Removal of POC
Uterus evacuation
Biannual compression
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16
Q

When would miscarriages be defined as ‘recurrent

A

Miscarriage on 3 or more consecutive occasions

17
Q

What is the probablitity of a live birth with the nect pregnancy after 3 miscarriages

A

40-50 percent

18
Q

What investigations should be done in people with recurrent miscarriages

A
Karyotyping both parents
Glucose tolerance
TSH
T4
hysteroscopy
HSG
Laparoscopy
Intra venous pyelogram
19
Q

What is an ectopic pregnancy

A

Implantation of the conceptus outside the uterine cavity

20
Q

What is the incidence of an ectopic pregnancy

A

1 in 300

recurrence rate is 10-15 percent

21
Q

How many women who have an ectopic pregnancy will be subfertile/infertile

22
Q

What make it more likely to have an ectopic pregnancy

A
Chlamydial or gonoccocal salpingitis
Previous tubak surgery
Endometriosis
IUCD
previous tubal ligation
IVF
increased parental age
23
Q

Clinical features of an ectopic pregnancy

A

Amenorrhoea
Lower abdo pain
Vaginal bleeding - three most common symptoms

Shoulder tip pain, shock, syncope, abdo guarding, cervical excitation, adnexal tenderness, bulky uterus

24
Q

Where are the possible sites of an ectopic pregnancy

A
Isthmal
Ampullary
Interstitial
Ovarian
Peritoneal
Cervical
25
What are the dangerous of an ectopic pregnancy
Intraperitoneal bleeding- potentially fatal Tubal rupture Tubal abortion
26
What investigations should be done in suspected ectopic pregancies
Urine b hcg Serun b hcg Transvaginal ultrasounf diagnostic laparoscopy
27
What is the treatment of an ectopic pregnancy
Laparascopic salpingectomy or salpingotomy IM methotrexate (or intratubal injection) Conservative management Laparotomy if ruptured
28
What is a hydratiform mole
Developmental anomaly of the trophoblast or placental in which there is a local or general vesicular change in the chorionic villi
29
What are the clinical features of a hydratiform mole
``` Amernorrhoea Vaginal bleeding Uterus larger than dates doughy uterus fetal heart negative hyperemesis Pre eclampsia ```
30
What types of moles are there
complete and incomplete/partial complete have ahigher risk of becoming a choriocarcinoma
31
What is the difference between an complete an partial mole
Complete - one or two sperm fertilise and egg which has lost its DNA Partial- one or two sperm fertilise an egg with DNA
32
Where are hydratiform moles more common
SE asia - about 1 in 150 - 1 in 500 In UK incidence is about 1 in 1000-2000
33
What investigations should be done in suspected hydratifrom moles
Urinary and serum B HCG Ultrasound CXR
34
What is seen on ultrasound in moles
snowstorm appearance | theca lutein ovarian cysts
35
How is a mole treated
``` Evacuation of uterus Urinary and serum b hcg and follow up Contraception to avoid pregnancy during follow up Hysterectomy if family complete persistant disease may require chemo ```
36
What can cause cervical incompetence
``` dilatation during top cone biopsy of cervix cervical amputation exposure to DES idiopathic in 25 percent ```
37
How can cervical incompetence be treated
Shirodhkar suture or Mcdonald suture At 14 weeks risk of ROM and infection removed at 36 weeks of gestation or early labour - whichever is first