Blood Flashcards Preview

HSCI100 > Blood > Flashcards

Flashcards in Blood Deck (36):
1

functions

- transportation: oxygen, nutrients, wastes, co2, hormones, etc.
- defense: against pathogens
- regulatory: body temp, water-salt balance, body pH

2

albumins

plasma protein

- for plasma osmotic pressure and transport

3

globulins

plasma protein

- transport lipids + fat-soluble vitamins
-some are antibodies

4

fibrinogen

blood clot formation

5

hematopoieisis

process of blood stem cell differentiation

6

rbc's

lacks nucleus, few organelles, shape increases surface area, hemoglobin molecule (each one binds 4 O2)

7

rbc production cycle and negative feedback

red bone marrow -> increased oxygen delivery to tissues -> inhibits erythropoeitin (EPO) release -> decreased oxygen delivery to tissues -> kidney EPO released -> old cells destroyed by liver/spleen -> epo increase -> production

8

anemia

too few rbc's/hemoglobin

9

sickle-cell anemia

genetic, rbc's sickle-shape that tend to rupture

10

hemolytic disease of the newborn

incompatible blood types -> rupturing of blood cells in a baby before and after birth

- Rh- mother + 2nd(+) Rh+ baby

11

wbc

red bone marrow, nucleus, production regulated by colony-stimulating factor (CSF), also found in tissues, immune system, etc.

12

eosinophil

granular wbc stained by eosin (red)
-small %
- large granules function in parasitic worm infections
- allergies

13

basophil

granular wbc stained by basic dyes (blue)
- small %
- histamine (attracts other wbcs, dilates blood vessels)

14

neutrophil

granular wbc unstained
- 50-70%
- phagocytosis
-component of pus

15

lymphocyte (B/T-cells)

- agranular
- 25-35%
- develops B and T cells for immune cystemd

16

monocyte

- in tissues
- macrophages use phagocytosis

17

severe combined immunodeficiency disease (SCID)

inherited
- wbc's lack enzyme to fight any infection

18

leukemia

groups of cancers affect wbc's

19

infectious mononueclosis

"kissing disease"
- epstein-barr virus (EBV) infects lymphocytes
- fatigue, sore throat, swollen lymph nodes

20

platelets

- megakaryocyte fragments
- blood proteins thrombin + fibrinogen for blood clotting

21

blood clot process step 1

injured cells in vessel walls and platelets release clotting factors

22

blood clot process step 2

clotting factors convert inactive blood protein to prothrombin activator

23

blood clot process step 3

prothrombin activator: prothrombin -> thrombin (liver)

24

blood clot process step 4

thrombin: fibrinogen -> fibrin (liver)

25

blood clot process step 5

fibrin network traps rbcs and platelets, forming blood clot

26

thrombocytopenia

platelets # low

27

thromboembolism

when a clot forms (thrombus) and breaks off from its origin site (embolus) and plugs another vessel

28

hemophilia

genetic disorder
- unable to properly clot internally and externally

29

antigen

foreign substance (eg polysaccharide, protein) that stimulates immune response

30

antibody

proteins made in response to antigen (binds to it to eliminate)

- very specific, numerous variety

31

type A

- A antigen
- Anti-B
- Receives A, O

32

type B

- B antigen
- Anti-A
- Receives B, O

33

type AB

- AB antigen
- none
- receives all

34

type O

- no antigen
- Anti-A/B
- receives O

35

Rh factor

Rh antibodies develop when exposed to Rh factor from another (fetus)

36

hemolytic disease of the newborn prevention

- Rh- women given injection of anti-RH antibodies