Blood Hemostasis Flashcards
(32 cards)
Type A
A antigens
B antibodies
Type B
B antigens
A antibodies
Type AB
universal recipient
AB antigens
no antibodies
Type O
universal donor
no antigens
AB antibodies
Hypoxia
oxygen deficiency at tissue level
Thrombus
stationary blood clot that may occlude a vessel
Hemophilia
hereditary
inability to clot blood
blood is part of the ___ system. It is a type of __ __ __
cardiovascular
liquid connective tissue
Functions
transportation: O2, CO2, waste, heat
regulation: pH buffer, body temp, water vol.
protection: blood loss, pathogenic invasion
Components of blood
solid and liquid
55% liquid
45% solid: 44% RBC, 1% WBC + platelets
Blood plasma
extracellular, straw colored
dissolved substances, RBC, platelets
92% H2O
8% dissolved: 7% plasma proteins, 1% other
7% plasma proteins
60% albumin, water content, osmotic pressure
36% globulin
4% fibrinogen, fibrin clot
Hematocrit
% RBC in blood sample (volume)
RBC count
RBC per cubic mm
WBC count
WBC per cubic mm 5-10,000/mm^3
WBCC>10,000 leukocytosis (infection)
WBCC<5,000 leukopenia, illness, disease, stress, drugs
Hemoglobin count
by weight
used for pediatrics
Erythrocytes
red blood cells
incompletely perforated doughnuts
biconcave disk
thin towards center (surface area and flex)
no nucleus
RBC function
carry oxygen
33% by weight is hemoglobin
Fe2+ iron
Agranulocytes
monocytes: largest phagocytosis
lymphocytes: smallest, live long, immunity/antibodies
Thrombocytes
platelets
cell fragments of megakaryoblasts
hemostasis
Blood group/ABO
if mixed cause agglutination
antigens on surface
RH grouping
pos: Rh antigens, no antibodies
neg: no antigens, develop Rh antibodies to Rh pos blood
erythroblastosis fetalis: rhogan
Platelet plug formation
platelets aggregate
in vessel break promotes clot
attach to rough surfaces, collagen, thrombocytes
seals small vascular breaches
Blood coagulation
complex biochemical cascade
most effective hemostasis
turn soluble protein (fibrinogen) into insoluble fiber (fibrin)
