Flashcards in Blood Lecure 1 / Ch 6 Leukocytes of Lymphoid Heritage Deck (15)
T and B Lymphocytes
• They add specificity to the
immune systems attack
• Destroying infected cells to
prevent spread of virus
• Retaining a memory of
exposure to specific
Location of T Lymphocytes ?
- Originate in Bone Marrow
- Maturation in the Thymus
- Once matured, live in the Lymph Nodes,
Spleen, & Tonsils. Here they wait, for APC
to introduce them to antigens.
Location of B Lymphocytes
- Maturation in the Bone Marrow
- Live in the Lymphatic nodes & ducts, here
they wait for antigen.
- Once stimulated by antigen they proliferate
and become Plasma Cells
- Capable of producing immunoglobulins
(antibody) to coat the specific antigen
– Live a few days to weeks
- AKA Thrombocytes
- Vital in hemostasis by coagulation
Platelet Life Span
- Develop in Bone Marrow from
- Circulate intravascularly
- migrate into the spleen and spend some
time here before returning to the
- 9 to 12 days
Retention of 1/3 of the platelets in the spleen is called what ?
Un-activated Platelet Shape
Activated Platelet Shape
round spheres with extended
pseudopods and spikes
Normal = 150,000 - 450,000 / μL
(AKA: thrombocythemia) Increased number of platelets.
Decreased number of platelets.
Testing platelets after CPB. Platelet count is not a good test, Platelet aggregation is a better test. POC tests are faster because?
They use whole blood
Heparin induced Thrombocytopenia