Blood Lecure 1 / Ch 6 Leukocytes of Lymphoid Heritage Flashcards Preview

CVPR 330 Blood > Blood Lecure 1 / Ch 6 Leukocytes of Lymphoid Heritage > Flashcards

Flashcards in Blood Lecure 1 / Ch 6 Leukocytes of Lymphoid Heritage Deck (15):
1

T and B Lymphocytes

• They add specificity to the
immune systems attack
• Destroying infected cells to
prevent spread of virus
• Retaining a memory of
exposure to specific
antigens

2

Location of T Lymphocytes ?

- Originate in Bone Marrow
- Maturation in the Thymus
- Once matured, live in the Lymph Nodes,
Spleen, & Tonsils. Here they wait, for APC
to introduce them to antigens.

3

Location of B Lymphocytes

- Maturation in the Bone Marrow
- Live in the Lymphatic nodes & ducts, here
they wait for antigen.
- Once stimulated by antigen they proliferate
and become Plasma Cells

4

Plasma Cells

- Capable of producing immunoglobulins
(antibody) to coat the specific antigen
– Live a few days to weeks

5

Platelets

- AKA Thrombocytes
- Enucleated
- Vital in hemostasis by coagulation

6

Platelet Life Span

- Develop in Bone Marrow from
Megakaryocytes.
- Circulate intravascularly
- migrate into the spleen and spend some
time here before returning to the
bloodstream.
- 9 to 12 days
-

7

Retention of 1/3 of the platelets in the spleen is called what ?

Sequestration

8

Un-activated Platelet Shape

Small spheres

9

Activated Platelet Shape

round spheres with extended
pseudopods and spikes

10

Platelet Quantity

Normal = 150,000 - 450,000 / μL

11

Thrombocytosis

(AKA: thrombocythemia) Increased number of platelets.

12

Thrombocytopenia

Decreased number of platelets.

13

Testing platelets after CPB. Platelet count is not a good test, Platelet aggregation is a better test. POC tests are faster because?

They use whole blood

14

HIT

Heparin induced Thrombocytopenia

15

HITT

Heparin induced thrombocytopenia and
thrombosis