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Flashcards in bone and joint infections Deck (26)
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1

define osteomyelitis

inflammation of the bone marrow and surrounding bone

2

what are the most common organisms associated with osteomyelitis

staph aureus
coagulase negative staph
strep
gram negative rods
anaerobes

3

what are the 3 most common routes of infection of osteomyilitis

1. hematogenous spread of bacteria
2. direct infection of bone form adjacent infection
3. secondary infection due to vascular insufficiency

4

differentiate between acute and chronic osteomyelitis

acute osteo = symtoms less 2 than weeks
chronic osteo = recurrent or symptoms longer than 4 weeks

5

what are goals of treatment of osteomyelitis

1. resolve infection
2. prevent amputation
3. prevent chronic, reoccurring infection

6

define septic arthritis

infection of a joint

7

what are the most common organisms associated with septic arthritis

nongonococcal arthritis
gonococcal arthritis
(also viruses fungi and mycobacteria)

8

If gram negative rods are suspected in osteomyelitis, what therapy should be used

3rd and 4th gen cephalosporins

9

what route of osteomyelitis infection may have anaerobic infection?
what should be used to treat it

adjacent site or vascular insufficiency
use clindamycin or metronidazole

10

what drugs cover MRSA

Vancomycin
Daptomycin
Linezolid
Clindamycin
Bactrim
(know first 3 well)

11

how long should a patient be treated for acute osteomyelitis

4-6 weeks, iv initially

12

how long should a patient be treated for chronic osteomyelitis

6-8 weeks IV then 3-12 months PO

13

what is the term potential for rapid joint destruction with irreversible loss of function

rheumatologic emergency

14

what type of arthritic infection involves fever, loss of joint function for 1-2 weeks, usually in knee in people over 30

nongonococcal arthritis

15

what usually causes nongonococcal arthritis

S. aureus

16

what organism causes gonococcal arthritis

Neisseria gonorroeae

17

what are some risk factors for gonococcal arthritis

1. female
2. low ses
3. nonwhite
4. men who have sex with men
5. multiple partners
6 illicit drug use

18

what type of septic arthritis often appears on more than one spot

gonococcal arthritis

19

what is the classic presentation of gonococcal arthritis

1. dermatitis
2. tenosynovitis
3. migratory infection

20

how is septic arthritis managed

1. prompt joint drainage
2. antibiotics

21

what is recommended for nongonococcal therapy

vancomycin for gram positive
ceftazidime or cefipime for gram negative

22

what 3 drugs can be used for nongonococcal arthritis infection if there is a significant penicillin allergy and it is a gram negative rod culture

1. aztreonam
2. ciprofloxacin
3. lefofloxacin

23

how long should nongonococcal arthritis be treated

2 weeks IV 2 weeks PO; 4 weeks total

24

how long should gonococcal arthritis be treated

10-14 days

25

what is the referred treatment for gonococcal arthritis

ceftriaxone

26

what type of gram stain is a gonococcal infection

gram negative cocci