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Flashcards in fungal infection Deck (25)
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1

what single cell organisms are reproduced primarily by budding

yeasts

2

what type of fungi can cause superficial or invasive infections

yeasts

3

what exists as either a yeast or a mold

dimorphic fungi

4

what are multi-cellular colonies that reproduce primarily by disseminating spores

molds

5

what primarily causes invasive disease through inhalation

molds

6

what are 3 factors that determine how a dimorphic fungi exists

1. pathogen
2. site of growth (host vs. lab)
3. temperature

7

what are two different types of fungus yeasts

1. candida
2. cryptococcus

8

what are two different types of dimorphic fungi

1. histoplasma
2. blastomyces

9

what is one class of fungus mold

aspergillus

10

what are two types of fungi pathogenicity

primary - may cause disease in healthy or immunocompromised disease
2. opportunistic - immunocompromised only

11

what are 3 types of opportunistic fungi

1. candidiasis
2. aspergillosis
3. cryptococcosis

12

what are 2 types of primary (pathogenic fungi)

histoplasmosis
blastomycosis

13

what is considered both a pathogenic and opportunistic fungi

cryptococcosis

14

what are 5 types of immunocompromised patients

1. diabetic
2. lymphoreticular/ hematologic malignancies
3. HIV
4. immunosuppressive therapy (including broad spectrum antibiotics)
5. organ transplants

15

what are the 6 most important candida pathogens?

1. C. albicans - 50% of all candida species
2. C. glabrata - common in adults > 65 and res to azoles
3. C. krusei - intrinsically resistant to azoles
4. C. tropicalis - common in deep tissue infection
5. C. parapsilosis - 2nd most common; often in NICU pts
6. C. lusitaniae - rare; often in cancer patients

16

which type of candida pathogen makes up 50% of all candida species

C. albicans

17

which type of candida pathogen is common in adults > 65 yo. and resistant to azoles

C. glabrata

18

which type of candida pathogen is intrinsically resistant to azoles

C. krusei

19

which type of candida pathogen is common in deep tissue infection

C. tropicalis

20

which type of candida pathogen is 2nd most common and often in NICU pts

C. parapsilosis

21

which type of candida pathogen is rare and often in cancer patients

C. lusitaniae

22

what type of candida is susceptivle to azoles

candida albicans

23

candidiasis typicaaly acquired

via the GI tract; but through IV catheters (to bloodstream) are also possible

24

what are the risk factors for candidiasis (7)

1. multiple antibiotics
2. vascular accesses
3. parenteral nutrition
4. ICU stay greater than 7 days
5. candida colonization
6. renal failure
7 major abdominal surgery

25

where can mucosal colonization of candida take place

1. oro-pharyngeal
2. upper and lower GI
3. genitals
4. urinary tract.