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Flashcards in infective endocarditis 2 Deck (22)
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1

what are the two most common strep organisms that cause IE

Viridans Strep
S. Bovis

2

what is the treatment for patients over 65 or with native valve IE with no resistance

penicillin G
or
Ceftriaxone

3

what is the duration of therapy for patients over 65 or with native valve IE with no resistance

4 weeks

4

what is the duration of therapy for patients on penicillin G or ceftriaxone plus gentamicin for native valve strep IE

2 weeks

5

who can't use penicillin G or ceftriaxone plus gentamicin for native valve strep IE

pts. with ascess or with a CrCl less than 20

6

what is recommended when patients are unable to tolerate beta lactam antibiotics with a native valve IE

vancomycin

7

what is the duration of vancomycin for treating a native valve strep IE

4 weeks

8

what is the recommended treatment for patients with a native valve strep IE and is penicillin intermediate/ resistant and durations?

still can use penicillin G or ceftriaxone for 4 weeks
plus gentamicin therapy for 2 weeks
OR
4 weeks of Vancomycin

9

what is recommended for PCN susceptible patients strep IE and a prosthetic valve and for what duration?

penicillin G or ceftriaxone for 6 weeks
with or without gentamicin for 2 weeks

10

what is recommended for PCN susceptible patients strep IE and a prosthetic valve unable to tolerate beta lactam antibiotics and for what duration?

vancomycin for 6 weeks

11

what is recommended for PCN intermediate/ resistant patients strep IE and a prosthetic valve unable to tolerate beta lactam antibiotics and for what duration?

vancomycin for 6 weeks

12

what is recommended for PCN intermediate/ resistant patients strep IE and a prosthetic valve and for what duration?

penicillin G or ceftriaxone for 6 weeks
PLUS
Gentamicin for 6 weeks
(vanc monotherapy is preferred)

13

what is the recommended treatment for patients with a native valve, oxacillin susceptible staph IE and duration

nafcillin for 6 weeks
with or without gentamicin for 3-5 days

14

what is the recommended treatment for patients with a native valve, oxacillin susceptible staph IE and duration for penicillin allergic patients

cefazolin for 6 weeks
with or without gentamicin for 3-5 days
(vancomycin is preferred)

15

what is the recommended treatment for patients with a native valve, oxacillin resistant staph IE and duration

vancomycin for 6 weeks

16

what is the alternative treatment for patients with a native valve, oxacillin resistant staph IE and duration

daptomycin

17

what is another name for oxacillin resistant staph strains

MRSA

18

what is another naim for oxacillin susceptible staph

MSSA

19

what is native valve staph IE treatment is avoided if a patient has a anaphylaxis reaction to penicillin

cefazolin
(go with vanc)

20

what is the recommended treatment for patients with a prosthetic valve, oxacillin susceptible staph IE and duration

nafcillin or oxacillin for 6 weeks or longer
PLUS
Rifampin for 6 weeks or longer
PLUS
Gentamicin for 2 weeks

21

what is the recommended treatment for patients with a prosthetic valve, oxacillin resistant staph IE and duration

vancomycin for 6 weeks or longer
PLUS
Rifampin for 6 weeks or longer
PLUS
Gentamicin for 2 weeks

22

what is the only condition where vancomycin is used in combination with gentamicin

oxacillin resistant staph (MRSA) IE in a prosthetic valve