Bones review 2 Flashcards Preview

Pathology 372 > Bones review 2 > Flashcards

Flashcards in Bones review 2 Deck (24):
1

List 3 forms of chondrodysplasia/skeletal dysplasias:

  1. Dwarfism
  2. Angular deformities
  3. Amelia (complete limb loss)
  4. Hemimelia (missing part of a limb)

2

  1. What condition is chondrodysplasia most similar to and why?
  2. How do these two conditions differ?

  1. Rickets - Chondrodysplasia is a condition associated with the thickening of the growth plate as well.
  2. Chondrodysplasia is not associated with any nutritional deficiencies, such as Ca, P or vitamin D.

3

What is the term for a mandible that expands past where it should?

Prognathism

4

What is the term for too short of a mandible?

Brachygnathism

5

What teratogen causes cyclopeia in sheep on the 14th day of gestation?

Veratrum californicum

6

Define osteochondrosis.

Focal defect in endochondral ossification.

7

Which areas of the bone are affected by osteochondrosis?

  1. Articular-epiphyseal complexes
  2. Physes (growth plates)

8

What is the condition called when a flap of articular cartilage breaks lose?

Osteochondrosis dissecans

9

Osteochondrosis develops because of an insufficient blood supply and necrosis of what?

Chondrocytes

10

Chondrodysplasias are all abnormalities of what?

Chondrodysplasias are abnormalities of cartilage, which leads to abnormal endochondral ossification and secondary bone deformities.

11

Osteochondrosis is typically a disease that mostly affects which types of animals?

Those grown for rapid, long bone growth

12

What is the mechanism of osteochondrosis dessicans?

  1. Premature vessel closure
  2. Ischemia at the AE complex
  3. Cartilage necrosis
  4. Focal EO failure
  5. Adjacent EO progression
  6. Deformation of articular surface
  7. Cartilage breaks free

13

What mechanism causes a net decrease in bone mass?

Osteoclastic activity exceeds bone production

14

What might cause osteoporosis?

  1. Disuse
  2. Nutritional deficiencies
  3. Hyperparathyroidism

15

What is a focal loss of bone?

Bone lysis

16

What is diffuse loss of bone?

Osteoporosis / osteopenia

17

Define hyperostosis.

Increased production of bone.

18

What conditions could cause hyperostosis to develop?

  1. Trauma (periosteal injury)
  2. Compression
  3. Neoplasm
  4. Chronic inflammation

19

What is osteosclerosis?

A failure of osteoclasis (decrease in the number and activity of osteoclasts)

20

What is osteopetrosis?

Diffuse osteosclerosis of trabecular (spongy) bone 

21

  1. What is this bone conditioned called?
  2. The failure of what caused this?

Q image thumb

  1. Osteopetrosis
  2. Osteoclasitic activity failed

22

What is the #1 cause of osteonecrosis?

Ischemia

23

Fracture through a growth plate will result in what?

Premature closure

24