Which part of the kidney receives a greater blood volume, medulla or cortex?
What are the layers of the filtering membrane of the glomerulus?
Fenestrated endothelial cells Glomerular basement membrane (double membrane) Podocytes (visceral epithelial cells)
Where does the nephrin reside?
Slit pore diaphragm
The glomerular filtration apparatus is a selective filter that prohibits the passage of which types of molecules?
Large Negatively charged
Where do juxtaglomerular cells reside?
What structure resides within the distal tubule?
Which cells produce renin?
An increase in SNGFR (single nephron glomerular filtration rate) can lead to what type of injury to those remaining glomeruli?
Hyperfiltration injury, which can lead to sclerosis and end-stage renal disease
Is the blood pressure through the glomerulus high or low?
List 5 functions of the kidney
1. Maintain acid/base balance 2. Regulate water volume 3. Maintain ion balance 4. Rid metabolic wastes (urea, creatinine) 5. Endocrine functions
How might a decrease in renal mass can lead to anemia?
Decreased erythropoietin production