Brachyspira and Treponema are known as ____
Brachyspira belongs to the family ____ and are obligate _____
what part of the body does Brachyspira colonize?
What is the most important species of Brachyspira?
What does Brachyspira hyodysenteriae cause and in what animal?
*affects actively growing pigs
What makes the Brachyspira cell wall different?
has a lipo-oligosaccharide
Brachyspira contains Hemolysin. The more ____ the bacteria, the more chance that it will be associated with bad disease
Brachyspira Hyodysenteriae is strongly ____ hemolytic
What virulence factor is necessary for Brachyspira and allows the bacteria to move through intestinal mucosa?
What are the most important reservoir for Brachyspira hyodysenteriae?
asymptomatic carrier pigs
How is Brachyspira transmitted?
what is the pathogenesis for Brachyspira?
edema, hypermia, hemorrhages
if the infection is bad enough it can lead to failure of colonic absorption
What is the major clinical sign of Brachyspira?
*normally bloody because of damage to enterocytes
What are the differentials for Brachyspira Hyodysenteriea that are hard to differentiate?
Salmonellosis and Lawsonia intracellularis
What species of Brachyspira causes avian intestial spirochaetosis?
Fecal samples for diagnosis of Brachyspira should not be allowed to ___
What is the special blood agar for Brachyspira?
*specific agar with several antibiotics incoorporated
The more virulent the strain of Brachyspira, the more ____ on blood agar
What disease does Lawsonia Intracellularis cause?
*in many different species, but mainly porcine
Lawsonia intracellularis are ____intracellular pathogens of enterocytes
What type of secretion system does Lawsonia have?
What are the reservoirs for Lawsonia?
intestinal tract and environment
How is Lawsonia transmitted?
fecal oral route
what is requires for Lawsonia to be infective?
interaction with unknown natural flora are required for disease
*If the animal has no bacteria in the GI tract then Lawsonia cannot cause disease
Lawsonia inhibits the host cell ____ process
*leads to more bacterial cells and proliferative lesions in the enteric mucosa
What antibody is predominant in Lawsonia infections?
True/False: vaccines work well against Lawsonia
*vaccines and antibiotics are effective against lawsonia
What bacteria causes rabbit syphilis?