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Flashcards in Pseudomonas Deck (36):
1

Pseudomonas is a gram negative bacteria that is a _____ aerobe

obligate 

2

Pseudomonas is extremely ______

opportunistic 

3

What is the main pathogenic species of Pseudomonas?

Pseudomonas Aeruginosa 

4

Pseudomonas is usually a ____ agent with significant____ resistance

usually a secondary agent

Antimicrobial resistance 

5

Pseudomonas likes to live in ____ poorly aerated environments such as surgery support bags and hoses in anesthetic machines 

wet

6

True/False: Pseudomonas can cause mastitis?

True 

usually via intramammary infusions 

7

Pseudomonas is motile via _____

flagella 

8

What virulence factor allows adherance to the respiratory mucosa for Psuedomonas?

outer membrane proteins 

and non fimbrial adhesins 

9

True/False: Pseudomonas has a remarkable capacity to adapt to and thrive in diverse ecological niches 

True 

10

Pseudomonas has a virulence factor that leads to ____ formation

biofilm 

11

True/False: Pseudomonas does not have a capsule

False

It is encapsulated 

12

What are the exotoxins of Pseudomonas and what are their characteristics?

Exotoxin A- inhibits protein synthesis

Exotoxin S and T- interferes with phagocytosis 

Exotoxin U- cytotoxic effect

Exotoxin Y- increases cAMP 

13

Which Pseudomonas exotoxins cause death of the cells that it is associated with?

Exotoxins U and Y 

14

What virulence factor of Pseudomonas is useful diagnostically and helps to protect the pseudomonas against free radicals?

Pigments (Pyocyanins)

*Pseudomonas is protected due to catalase and superoxide dismuate 

15

What is the Reservoir for Pseudomonas?

Soil, water, feces of normal animals- EVERYTHING 

16

Most infections of Pseudomonas are _____ to compromised hosts 

secondary 

*ex. illness or trauma allows pseudomonas to colonize. It is very opportunistic

17

What is the pathogenesis of Pseudomonas?

1. reduced normal flora allows bacteria to colonize (usually due to antimicrobial use)

2. adhere to the epithelial cell layer and reproduce 

3. Destroys epithelial cells and tissues (pyocyanin)

18

Where will you see Pseudomonas the most?

Ear infections! 

ottitis externa 

19

What animals are predisposed to Pseudomonas?

swimmers

breeds with long ears- ex. bassett hounds

breeds with hair in external ear canal

20

Other than ear infections, what other disease can Pseudomonas cause?

Lower urinary tract infection

*not very common

21

What can Pseudomonas cause in horses?

Metritis

*secondary to prolonged treatment with antimicrobials 

22

What does a skin infection of Pseudomonas look like?

Like this! 

A image thumb
23

Pseudomonas can cause pustular _____ skin lesions 

pyoderma 

24

Pseudomonas has caused a particular problem in farmed _____

mink 

*mortality 50% due to hemorrhagic pneumonia 

25

What granulomatous inflammation of the skin can Pseudomons cause?

Pseudomonal Botryomycosis 

*grape like appearance- little nodules under the skin 

26

What condition can Pseudomonas aeurginosa cause in sheep?

Fleece Rot of sheep

A image thumb
27

What humans are most suscptible to Pseudomonas infections?

Immunocompromised individuals

*especially burn victims 

28

What is the best way to prevent Pseudomonas?

Need to decrease the risk of secondary infection

*clean environment, clean and dry ears 

29

Pseudomonas is ____ hemolytic and ___ growing 

Beta hemolytic

Fast growing 

30

What is a characteristic of Pseudomonas that helps with diagnosis?

Odor!

*suppose to smell like grapes 

31

Pseudomonas is oxidase ____

positive 

32

True/False: Pseudomonas is susceptible to antimicrobials 

FALSE

highly resistant to microbials

33

What give the dark appearance of Pseudomonas on agar?

Pyocyonin turns the plate a dark color

A image thumb
34

Does Pseudomonas ferment the sugars in a TSI test?

no

*non fermenters. TSI appears red 

35

Is Pseudomonas lactose negative or positive on MacConkey Agar?

Lactose negative

*NO PINK COLOR 

36

What is the best treatment for Pseudomonas?

identify the predisposing factor and eliminate the source of the organism 

*Use hygienic practices. Keep endotracheal tubes and anethetic hoses clean