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MY Bacteriology FINAL > Brucella > Flashcards

Flashcards in Brucella Deck (38):
1

Is Brucella reportable?

YES

2

Brucella requires _____ for survival

animal host

*DOES NOT DO WELL IN ENVIRONMENT

 

3

What areas of the body are Brucella most associated with?

Reticuloendothelial and genital tract

4

What is the common manifestation of Brucella?

Abortion

Orchitis-inflammation of testicle

5

Brucella likes to cause ____

abortions 

6

True/False: Brucella can cause mastitis

True 

7

Brucella uses a type ___ secretion system for ____ survival

type IV secretion system

intramacrophage survival

8

smooth colonies of Brucella are more ___ than rough colonies

more virulent 

9

What is the most common route of transmission for Brucella?

Ingestion 

*tissue and fluid associated with abortion can also be infective 

10

True/False: Brucella can be transmitted in utero to progeny and vererally 

True

11

Brucella Pathogenesis:

1. Brucella penetrates intact mucosal surfaces

2. macrophage uptake

3. intracelluar survival (type 4 secretion system)

4. localization in retiuclo-endothelial system and reproductive tract

5. abortion 

12

What kind of inflammation does Brucella cause?

Granulomatous

*A lot of macrophages in the area 

13

Brucella Melitensis can lead to what? 

Necrotic Cotyledon 

A image thumb
14

What does Brucella cause in males?

enlargment of epididymis- painful scrotum

orchitis

15

True/False: once a female has an abortion they are normally immune from Brucella

True

16

Anytime you think Brucella, think ______

ABORTION 

17

What are some of the common extragenital manifestation of Brucella?

Swine- arthritis

Dogs- meningoencephalitis, osteomyelitis

Cattle: hygromas (callus of the knee cap)

Horses: poll evil- not common at all

picture: hyogroma in the knee cap of a cow

A image thumb
18

What is an extragenital manifestation of Brucella in humans?

Undulant Fever 

19

How do humans usually aquire Brucella?

handling tissue containing Brucella

ex. aborted fetuses, fluids, non pasteurized milk

*Veterinarians are at risk 

20

What is the main species of Brucella that can infect humans?

Brucella Melitensis 

21

___ animals are more susceptible to Brucella

Mature 

22

How to control Brucella infection in a swine herd?

do not have breeding swine confined to same pen

eliminate infected boars 

minimize exposure to aborted tissues 

23

True/False: Brucella mainly effects younger individuals

False

*older individuals are more susceptible 

24

What is the unique way that dogs can spread Brucella?

urine 

25

Do antibodies help with Brucella infections?

low levels- kill bacteria

high levels- interfere with complement

26

Brucella likes to live inside ____

phagocytes 

27

Effective immunity to Brucella is primarily ____

cell mediated 

28

What Brucella species infectes what animals?

B. abortus- Cattle

B. suis- Swine

B. Melitensis- Goats and sheep

B. canis- dogs

29

What is the best sample for diagnosis of Brucella?

Fetal contents 

30

What vaccines are available for Dogs and Swine with Brucella?

no vaccines for dogs and swine 

31

True/False: great care should be employed when working with tissues and fluids infected with Brucella

True

*Be very careful 

32

True/False: Gram stain is the best way to diagnose Brucella

False

Immunofluorescence is the best way

*Slow and hard to grow in agar 

33

True/False: Brucella is hemolytic

False

*non hemolytic 

34

True/False: Brucella is urease positive 

True 

35

Brucella ____ ring test is positive if a purple ring develops 

milk

*purple ring develops in top of cream 

36

What is the best treatment for Brucella in livestock?

No treatment for Brucella is attempted in livestock! 

*potential problems of maintaining infected animals during eradication programs

37

What is the best treatment for Brucella in dogs?

neutering affected animals

antibiotic therapy 

38

What are the different ways to prevent Brucella?

Immunization alone- reduces abortions but does not eradicate bacteria

Immunization followed by test and slaughter- if females are postive they are killed

Testing and removal of infected animals without immunization- depopulation of entire swine, sheep or goat population is a good way to get the bacteria under control