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Flashcards in Burkholderia Deck (39):
1

Burkholderia are gram negative, aerobic rods that are ____ positive

catalse 

2

What two species are important for Burkholderia?

B. mallei

B. pseudomallei 

3

True/False: Burkholderia causes a pyogranulomatose disease 

True 

4

___ organisms of Burkholderia are necessary to cause diseaes. They are a category B agent and are _____

Few organisms are needed to cause disease

REPORTABLE 

5

True/ False: Burkholderia mallei can be bioweaponized 

True

 

6

What does Burkholderia mallei cause in horses? 

Glanders

*can also affect other species such as cats but they are dead end hosts 

7

True/ False: Horses are dead end hosts in Burkholderia mallei

False

8

Burkholderia mallei is a _____ disease

REPORTABLE 

9

Burkholderia Mallei is characterized by the formation of nodules and ulcers in the ____ or skin 

respiratory tract

10

What type of secretion system does Burkholderia Mallei use?

Type III and IV secretion system

11

What are the reservoir hosts for Burkholderia Mallei?

Equids- HORSES

12

Burkholderia Mallei is called a true ___ because it needs a host to survive and cannot live in the envrionment for very long 

parasite 

13

What is the main transmission for Burkholderia Mallei?

Ingestion of contaminated feed and water 

14

What is common in males horses with Burkholderia Mallei?

Glanderous orchitis

*inflammation of the testicles

15

True/False: Burkholderia Mallei is normally a chronic, disseminated debilitating disease 

True 

16

When you see Glanders in the skin it is called ____

Farcy 

*Cutaenous Glanders = Farcy 

17

True/False: Glanders is not fatal 

 False

*Acute infection tends to end fatally in about 2 weeks 

18

Farcy (skin abscesses) tend to occur in the ____ infection of Glanders 

Chronic 

19

What are some signs of Glanders?

Fever, nasal discharge 

A image thumb
20

Is Burkholderia Mallei zoonotic?

YES- usually traced to an ill horse 

21

What disease does Burkholderia Pseudomallei cause?

Pseudoglanders 

22

Is Burkholderia Pseudomallei a reportable disease?

YES

23

What are some differences between Burkholderia Mallei and Pseudomallei?

Pseudomallei has a higher tendency to disseminate

Pseudomallei is a saprophyte and can survive in the environment, while Mallei does not

24

Burkholderia Pseudomallei are motile via ____

Flagella 

25

What bacteria causes Meliodiosis?

Burkholderia Pseudomallei

26

Meliodosis is similar to Glanders but affects a ____ host range

wide

*but mainy sheep and goats 

*severe in rodents 

27

How does melioidosis present in humans?

range from subclinical to rapidly fatal 

28

How does Pseudomallei perpetuate itself in the environment 

Adheres to ameobas

29

What secretion system does Burkholderia Pseudomallei have?

Type III and IV secretion system 

30

What is the reservoir for Burkholderia Pseudomallei?

soil and water (amoeba)

they like heavy rainfall

31

Melioidosis is a more disseminated disease than Glanders and in humans is known as ____

Whitmores disease 

*viatnamese time bomb- may develop disease months to years after infection

32

Burkholderia pseudomallei is _____, while Burkholderia mallei is non _____

pseudomallei is motile

mallei is non motile 

33

What special agar is used with Burkholderia?

Cepacia Agar 

A image thumb
34

What does Burkholderia pseudomallei cause on MacConkey agar?

wrinkled colonies

A image thumb
35

True/False: Once infected, an animal cannot become infected again with Burkholderia

False

*Those that recover are not protected 

36

For treatment of Glanders, Any animal that reacts to the screening tests should be ____

destroyed 

37

____ feeding and watering is discouraged for control of Glanders 

communal 

38

Treating Equids with Glanders is ____

DISCOURAGED

*destruction of animals is the recommended course of treatment 

39

there are not commercial _____ available for Glanders or Melioidosis

vaccines