Burkholderia are gram negative, aerobic rods that are ____ positive
What two species are important for Burkholderia?
True/False: Burkholderia causes a pyogranulomatose disease
___ organisms of Burkholderia are necessary to cause diseaes. They are a category B agent and are _____
Few organisms are needed to cause disease
True/ False: Burkholderia mallei can be bioweaponized
What does Burkholderia mallei cause in horses?
*can also affect other species such as cats but they are dead end hosts
True/ False: Horses are dead end hosts in Burkholderia mallei
Burkholderia mallei is a _____ disease
Burkholderia Mallei is characterized by the formation of nodules and ulcers in the ____ or skin
What type of secretion system does Burkholderia Mallei use?
Type III and IV secretion system
What are the reservoir hosts for Burkholderia Mallei?
Burkholderia Mallei is called a true ___ because it needs a host to survive and cannot live in the envrionment for very long
What is the main transmission for Burkholderia Mallei?
Ingestion of contaminated feed and water
What is common in males horses with Burkholderia Mallei?
*inflammation of the testicles
True/False: Burkholderia Mallei is normally a chronic, disseminated debilitating disease
When you see Glanders in the skin it is called ____
*Cutaenous Glanders = Farcy
True/False: Glanders is not fatal
*Acute infection tends to end fatally in about 2 weeks
Farcy (skin abscesses) tend to occur in the ____ infection of Glanders
What are some signs of Glanders?
Fever, nasal discharge
Is Burkholderia Mallei zoonotic?
YES- usually traced to an ill horse
What disease does Burkholderia Pseudomallei cause?
Is Burkholderia Pseudomallei a reportable disease?
What are some differences between Burkholderia Mallei and Pseudomallei?
Pseudomallei has a higher tendency to disseminate
Pseudomallei is a saprophyte and can survive in the environment, while Mallei does not
Burkholderia Pseudomallei are motile via ____
What bacteria causes Meliodiosis?
Meliodosis is similar to Glanders but affects a ____ host range
*but mainy sheep and goats
*severe in rodents
How does melioidosis present in humans?
range from subclinical to rapidly fatal
How does Pseudomallei perpetuate itself in the environment
Adheres to ameobas
What secretion system does Burkholderia Pseudomallei have?
Type III and IV secretion system
What is the reservoir for Burkholderia Pseudomallei?
soil and water (amoeba)
they like heavy rainfall
Melioidosis is a more disseminated disease than Glanders and in humans is known as ____
*viatnamese time bomb- may develop disease months to years after infection
Burkholderia pseudomallei is _____, while Burkholderia mallei is non _____
pseudomallei is motile
mallei is non motile
What special agar is used with Burkholderia?
What does Burkholderia pseudomallei cause on MacConkey agar?
True/False: Once infected, an animal cannot become infected again with Burkholderia
*Those that recover are not protected
For treatment of Glanders, Any animal that reacts to the screening tests should be ____
____ feeding and watering is discouraged for control of Glanders
Treating Equids with Glanders is ____
*destruction of animals is the recommended course of treatment
there are not commercial _____ available for Glanders or Melioidosis