Cartilage Flashcards

(45 cards)

1
Q

what are the connective tissues divided into

A

embryonic, soft, hard, and special connective tissue

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2
Q

what is type I

A

most abundant widely distributed

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3
Q

what is type II

A

hyaline and elastic cartilage

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4
Q

what is type III

A

recticual fibres

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5
Q

what is type IV

A

found in the basal lamina (does not form fibrils)

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6
Q

what is the composition connective tissue

A

semi rigid connective tissue
cartilage is avascular

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7
Q

how does cartilage get its nutrients

A

blood vessels surrounding connective tissue by diffusion through ECM

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8
Q

what does the cartilage lack

A

lacks lymphatic vessels and nerves

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9
Q

what are chondrocytes apart of

A

cells of cartilage

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10
Q

how is the extracellular cartilage shaped

A

amorphous (defined shapes)

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11
Q

what is type II fibres responsible for

A

provide mechanical stabillity

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12
Q

what allows deformation by compressive pressures

A

GAG’s and proteoglycans which attract water

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13
Q

what does chondroblats synthesize

A

ground substance and fibrous extracellular material

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14
Q

what does cartilage formation start with what

A

embryonic staellate mesenchymal cells

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15
Q

what does mesenchymal dfferentatie into

A

chondroblasts

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16
Q

what does multiplcation of chondroblasts forms

A

clusters 4 to 6 cells

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17
Q

what condroblasts mature into what

A

chondrocytes

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18
Q

what does chondrocytes maintian what

A

cartilage matrix

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19
Q

what are the stages of cartilage growth and where does it happen

A

appositional growth - at the edge
intersitial growth - within the matric

20
Q

what does the perichondrium form

A

chondrogenic cells

21
Q

what does chondorgenic cells differeinate into

A

chondroblasts

22
Q

what do chondroblasts deposit

A

layers of the matrix at the periphery of the cartilage

23
Q

what does the later stages of cartilage development

A

increases the thickness by appoisitonal growht

24
Q

what does the intersitial growth

A

by the mitosis of chondrcytes

25
what does chondrotes divide and secrete in intersitial growth
matrix components and then move apart and become isolated in their individual lacunae
26
what time does intersitial growth ocucr
ealry phases of cartialg formation
27
how does cartilage repair if small injury
be repaired by activity of chondrogenic cells of perichondrium these cells differentiate into chondroblasts migrate to the injured area and repair the defect by producing new cartilage matrix
28
how does cartilage repair if large
perichondrial cells cannot repair instead perichondrial fibroblasts produce a scar of dense connective tissue that fills the defect in the cartilage
29
type of collagen fibres for hyaline
type II fibres
30
type of collagen fibres for fibrocartialge
type I + II Fibres
31
type of collagen fibres for elastic cartialge
type II fibres and elastic fibres
32
which type of cells have a perichondrium
Hyaline - expect articualr cartilage and epiphyseal plates Elastic - Does
33
What are the main cells of hyaline cartilage
chondroblasts and chondrocytes
34
what is the main cells for elastic
chondroblasts and chondrocytes
35
what is the main cells for fibrocartialge
chondrocytes and fibroblasts
36
type of fibres in ECM for hyaline
Type II collagen
37
type of fibres in ECM for elastic
Type II collagen and Elastic fibres
38
type of fibres in ECM for firbocartialge
Type I and Type II collagen
39
What cartilages undergoes calcification
Hyaline - during endochronral bone formation (old age) Fibrocartilage - during bone repair
40
Function of hyaline cartilage
resists compression provides low friction surface for joints strutucal support in respiratory foundation for development of foetal skeleton
41
functions for elastic cartilage
provides flexible support for soft tissue
42
function fibrocartialge
resists deformation under stress
43
where is hyaline found
trachea and bonrchi articulating , coastal and nasal cartilage circoid thyroid and arytenoid cartilages of larynx
44
where is elastic found
pinna of the ear, epiglottis and autiodry tube
45
where is fibrocartilage found
intervertebral disc , pubic symphysis, intra articular disc of the sternoclvaicular joint and intra particular disc of the tmd joint