Cell Membranes Flashcards
(25 cards)
Function of lipid bilayer
Provides barrier for water-soluble molecules
Function of membrane proteins
For carbohydrates to bond to these
Integral membrane proteins
Have hydrophobic regions of amino acids that penetrate or entirely cross the phospholipid bilayer
Transmembrane proteins
Have specific orientation, showing different ‘faces’ on each side of the membrane
Peripheral membrane proteins
Lack hydrophobic regions and are not embedded in the bilayer
Anchoring of restricted molecules
Either anchored to cytoskeleton or trapped within lipid rafts
Carbohydrate-bound lipid
Glycolipid
Carbohydrate-bound protein
Glycoprotein
Tight junctions
Link adjacent epithelial cells, restrict migration of membrane proteins and phospholipids, prevent substances from moving through intracellular space
Gap junctions
Facilitate communication between cells, made of connexons (specialised protein channels that span plasma membranes and protrude sightly).
Desmosomes
Dense plaques attached to both cytoplasmic fibres and to membrane cell adhesion proteins which bind to proteins of an adjacent cell
Diffusion
Random movement towards state of equilibrium (slow)
Factors that impact diffusion rates
Temperature, size, electrical charge, concentration gradient
The more lipid-soluble the molecules…
The faster they diffuse
Hypertonic
Dehydrated
Isotonic
Average
Hypotonic
Over hydrated
Three types of protein that use active transport
Uniport, symport, antiport
Primary active transport
Only cations such as sodium, potassium, and calcium
Secondary active transport
Uses established gradients to move substances (e.g. Symport system in intestinal cells)
Types of endocytosis
Phagocytosis, pinocytosis, receptor-mediated endocytosis
Pinocytosis
Used to acquire fluids from blood
Phagocytosis
Defends body from invasion by foreign cells
Receptor-mediated endocytosis
Highly specific pinocytosis