Multicellularity Flashcards
(18 cards)
Unicellular
Single cell, simple body composition, exposed cell body, short lifespan, damage can cause serious injury or death
Multicellular
More than one cell, complex organisation, division of labour, only outer cells are exposed, longer lifespan, potential for more complex behaviour, damaged cells may be replaced
Simple
Limited co-ordination and differentiation, may be unicellular or multicellular
Complex
Multicellularity required for survival, several distinct and differentiated cell types, generated by cen type specific genes and intricate coordination of development processes
Simple multicellularity
May enhance or protect from predation
Complex multicellularity
Only found in animals, land plants, brown algae, fungi, and red algae
Aggregative pathway
Separate cells converge and adhere to each other, occurs in response to adverse conditions, only associated with simple multicelularity, gives rise to spherical masses of spores/cysts, aggregate is formed of quiescent cells that don’t feed/divide
Motility
Transient step towards formation of the aggregate
Clonal pathway
Serial cell division without dispersion of sister cells resulting from changes in the cell cycle and ECM genes, more widespread and diverse, occurs in complex multicellularity and some simple multicollularity
Origin of multicellular life
Proliferating cells develop ability to switch between unicellularity and multicellularity, division of labour occurs, cells are locked in multicellular condition, development of organs, cells become dependent on other cell types
Requirements for embryonic development
Regulated cell cycle, regulated programmes of gene activity, cell differentiation, signal transduction, cell mobility and cohesion
Single cel organisms ancestral to animals possessed.
Eukaryotic cell cycle, ability to undergo cellular differentiation, cell signalling molecules, cadherin-mediated cell adhesion
Clonal multicellularity in animas is marked by…
Explosive diversification of transcription factor families and signalling molecules
Choanoflagellates
Closest living unicellular relative to animals, each cell consists of a cell body, flagellum, and a collar of actin-filled tentacles
Sponges
Multicellular animals composed of spicules and choanocytes
Chlamydomonas phases
Swimming phase (cells have flagella), non-swimming phase (flagella resorbed, cell divides)
Graded complexity within the volvocine algae enables…
Exploration of the mechanisms underlying the evolution of multicellularity
Cancer and multicellularity
Cancer causes loss of cooperation and altruism between cells, causing them to resemble and behave like unicellular organisms