CH 16-17 immune Responses Flashcards
Immune System
Immune System- Large, complex, and diffuse network of cells and fluids that penetrate into every organ and tissue.
It provides a multi layer defense against potential pathogens
What are the four major subdivisions of the immune system?
Four major subdivisions of immune system:
- Reticuloendothelial system (RES)
- Extracellular fluid (ECF)
- Bloodstream
- Lymphatic system
Reticuloendothelial System (RES)
Reticuloendothelial System (RES) Network of connective tissue fibers that interconnects other cells and meshes with the connective tissue network surrounding organs
Inhabited by phagocytic cells
Plasma
Plasma – 92% water, metabolic proteins, globulins, clotting factors, hormones, and all other chemicals and gases to support normal physiological functions
Erythrocytes
Red blood cells
Leukocytes
Leukocytes – White blood cells
– Granulocytes: lobed nucleus
– Agranulocytes: unlobed, rounded nucleus
Granulocytes
Agranulocytes
Both are types of white blood cells
– Granulocytes: lobed nucleus
– Agranulocytes: unlobed, rounded nucleus
Platelets
– clotting, inflammation
Hemopoiesis
Hemopoiesis – production of blood cells
Diapedesis
Diapedesis – migration of cells out of blood vessels into the tissues
Chemotaxis
Chemotaxis – migration in response to specific chemicals at the site of injury or infection
What does the Lymphatic System do?
- Provides an auxiliary route for return of extracellular fluid to the circulatory system
- Acts as a drain-off system for the inflammatory response
- Renders surveillance, recognition, and protection against foreign material
What is Lymph?
Lymphatic Fluid or Lymph is a plasma-like liquid carried by lymphatic circulation
Formed when blood components move out of blood vessels into extracellular spaces
Made up of water, dissolved salts, 2-5% proteins
Transports white blood cells, fats, cellular debris, and infectious agents
What are the Lymphoid organs?
Thymus – high rate of growth and activity until puberty, then begins to shrink; site of T-cell maturation
Lymph nodes – small, encapsulated, bean-shaped organs stationed along lymphatic channels and large blood vessels of the thoracic and abdominal cavities
Spleen – structurally similar to lymph node; filters circulating blood to remove worn out RBCs and pathogens
What is the cellular fingerprint?
Recognition proteins are capable of identifying which cells are your own (self) and which are viruses/foreign (not self)