Ch. 5- Integumentary Ststem Flashcards
(50 cards)
What is the largest organ system of the body that 16% of our body weight?
Skin
What is the body’s first line of defense?
Skin
What does the skin consist of?
Cutaneous membrane
- epidermis
- dermis
Accessory structures
What is the cutaneous membrane?
Epidermis (superficial layer)
- keratinized stratified squamous epithelium
Dermis (deep layer)
- CT
- extensive network of blood vessels and sensory receptors
What are the accessory structures?
Originate in dermis
Extend through the epidermis to skin surface
- hair
- nails
- multicellular exocrine glands
What is the hypodermis (subcutaneous layer)?
Also called superficial fascia
Deep to the dermis
Consists of
- loose CT
- adipose tissue
Separates into the mend from the deep fascia around other organs
What is the protection of the integumentary system consist of?
Protection of underlying tissues and organs against impact, abrasion, fluid loss, and chemical attacks
What does the integumentary system secrete?
Excretion of salt, water, organic waste (glands)
How does integumentary system maintain body temperature?
Insulation and evaporation
What does melanin do?
Protects tissue from UV radiation
What does Keratin do?
Protects against abrasion and acts as a water repellent
What does vitamin D3 do?
Increases calcium absorption
Where does the integumentary system store lipids?
Adipocytes
What does integumentary system detect?
Touch
Pain
Pressure
Pain
Vibration
Temp
What are keratinocytes?
Most abundant cells of epidermis
Produce keratin- a tough, fibrous protein
Held together by desmosomes
Organized into layers (strata)
Originate in the stratum germinativum and migrate to skin surface
What are melanocytes?
Found in the deepest layer of the epidermis (stratum germinativum)
Synthesize pick me melanin in vesicles
Vesicles transferred to keratinocytes
What are langerhans cells (epidermal dendritic cells)?
Arise from bone Marrow and migrate to the epidermis (stratus spinosum)
Participate in immune responses against micro organisms that penetrate the epidermis and superficial skin cancers
What are merkel cells (tactile cells)?
Modified epithelial cells
Located at the epidermal-dermal junction
Associated with a disk-like (tactile disc) sensory nerve endings
Respond to light touch and light pressure
When compressed they release chemicals that stimulate the tactile discs of sensory nerve endings
What is the epidermis?
Consists of keratinized stratified squamous epithelium
Avascular
Nutrients and oxygen are obtained via diffusion from capillaries in the dermis
Keratinocytes are the most abundant cells
What is thin skin?
Covers most of the body
Consists of four layers (strata) of keratinocytes
What is thick skin?
Found in areas were exposure to friction is the greatest
Includes:
- fingertips
- Palms
- sole of feet
Consist of five layers of keratinocytes
What are the five strata of keratinocytes from free surface to basal lamina?
Stratum Corneum
Stratum Lucidum (in thick skin)
Stratum Granulosum
Stratum Spinosum
Stratum Germinativum (Basale)
Mnemonic: can Lucy get some bagels
What is the stratum germinativum?
Basal layer
Has many germinative stem cells or basal cells
Attached to basal lamina by hemidesmosomes
Contains:
- keratinocytes
- melanocytes
- merkel/ tactile cells
What is the epidermal ridges of the stratum germinativum?
Downward projections of the epidermis into the dermis
The project between the dermal papillae of the papillary region
Increases the surface area