ch.23 urinary Flashcards

1
Q

What are the functions of the urinary system?

A

filter blood
regulate blood volume which alter bp
vitamin D and RBC synthesis
regulate pH

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2
Q

What are the organs of the urinary system?

A

2 kidneys
2 ureters
bladder
urethra

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3
Q

hilium

A

where the renal artery and nerves enter and where renal veins and ureter exist

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4
Q

What is the functional unit of the kidney?

A

nephron

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5
Q

What 2 structures make up the nephron?

A

renal corpuscle and renal tubule

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6
Q

glomerulus

A

filtrates and collects in capsular space then flows into the renal tubule

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7
Q

What are the two types of nephrons?

A

juxtamedullary and cortical

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8
Q

cortical nephron

A

have short loops of henle

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9
Q

juxtamedullary nephron

A

longer loops of Henle
concentrates urine

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10
Q

loop of henle

A

conducts urine w/in each nephron

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11
Q

What does the nephron empty into?

A

collecting duct

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12
Q

afferent arteriole

A

supplies blood to the glomerulus

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13
Q

efferent arteriole

A

drains the glomerulus

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14
Q

juxtaglomerular apparatus

A

site of renin production

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15
Q

kidney circulation

A

glomerulus–> efferent arteriole–> peritubular capillaries–> vasa recta–> interlobar v.–> arcuate v.–> renal veins

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16
Q

What are the 3 steps of urine formation?

A

-glomerulus filtration
-tubular reabsorption/secretion
-water conservation

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17
Q

glomerulus filtration

A

creates a plasmalike filtrate of the blood

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18
Q

tubular reabsorption

A

removes useful solutes from the filtrate, returns them to the blood

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19
Q

tubular secretion

A

removes additional wastes from the blood and adds them to the filtrate

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20
Q

water conservation

A

removes water from the urine and returns it to the blood and concentrates wastes

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21
Q

filtration

A

movement of fluid across the filtration membrane

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22
Q

What can pass through the filtration membrane?

A

water, small molecules, ions but proteins can’t

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23
Q

renal fraction

A

part of the total cardiac output that passes through the kidneys

24
Q

What is the renal blood flow rate?

A

1176 mL/min

25
glomerular filtration rate
same amount of filtrate produced each minute
26
What 3 components make up the filtration membrane?
-fenestrated endothelium -basement membrane -filtration slits
27
glomerular capillary pressure
BP inside the capillary moves fluid out of the capillary into bowman's capsule -50 mmHg
28
What is glomerular capillary pressure responsible for?
filtration
29
What is the cause of high glomerular pressure?
low resistance to blood flow in afferent arterioles and glomerular capillaries
30
What occurs when afferent arterioles are dilated?
increases pressure
31
What occurs when afferent arterioles are consricted?
pressure decreases
32
What occurs when efferent arterioles are constricted?
increase pressure
33
capsule pressure
the pressure of filtrate already in the lumen of capsule
34
What is capsule pressure responsible for?
reabsorption
35
blood colloid osmotic pressure
osmotic pressure caused by proteins in blood, favors fluid into the capillary
36
What occurs if blood colloid osmotic pressure is increased?
reabsorption increases
37
What occurs if the GFR increased?
urine output rises causes dehydration and electrolyte depletion
38
What occurs if the GFR is decreased?
wastes reabsorbed azotemia occurs
39
azotemia
buildup of wastes
40
myogenic mechanism
-kind of autoregulation that occurs when BP increases and it constricts the afferent arterioles to lower BP
41
tubuloglomerular feedback
occurs on the macula densa and it monitors the tubular fluid, it signals the juxtaglomerular cells to constrict the afferent arterioles to lower GFR
42
sympathetic control
decreases urine output which constricts afferent arterioles
43
renin angiotensin system
angiotensin II has widespread vasoconstriction to constrict afferent to lower BP
44
macula densa
cells of the distal convoluted tubule in contact w/ afferent arterioles
45
wastes
any substance that is useless to the body or present in excess of the bodys needs
46
What is the main waste?
urea
47
urea
formed by breakdown of proteins
48
uric acid
formed by breakdown of nucleic acid
49
proximal convoluted tubule
reabsorbs 65% of GF to peritubular capillaries -major site of reabsorption
50
What are the two routes for reabsorption?
transcellular and paracellular
51
transcellular route
through epithelial cells
52
paracellular route
between cells
53
transport maximum
limit to the amount of solute that the renal tubules can reabsorb
54
What occurs if all transporters are occupied?
excess solutes appear in urine
55
secretion
waste removal of urea, uric, ammonia
56
nephron loop
important for water conservation