Chapter 10 Flashcards

(51 cards)

1
Q

urine pathway

A

kidney to ureters to bladder to urethra

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2
Q

kidney structure and function

A

cortex is outer, middle slit is hilum

excretes waste

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3
Q

glomeruli

A

tufts in kidney form afferent arterioles

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4
Q

Kidney portal path

A

artery to afferent arterioles, to efferent arterioles then second capillaries

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5
Q

vasa recta

A

capillaries surrounding loop of henle

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6
Q

bowmans capsule

A

around glomerulus, leads to PCT then dec/ascending LOH, then DCT and collecting duct

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7
Q

detrusor muscle

A

bladders muscular lining, parasympathetic

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8
Q

internal sphincter

A

smooth muscle of bladder, contracted at normal state, involuntary

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9
Q

external sphincter

A

skeletal, voluntary

stretch receptors send message to NS to empty bladder

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10
Q

how does external sphincter signal bladder

A

PS neurons fire and detrusor muscles contract while internal muscles relax

we decide to relax or maintain external muscles and urinate

aided by abdominal muscles compression on bladder

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11
Q

micturition

A

external sphincter muscles urinate

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12
Q

osmoregulation

A

kidneys regulate BV and osmolarity

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13
Q

kidney filtration

A

blood is filtered as filtrate into bowmans space

uses starling forces for net flow into nephron and filter using glomerular pores based on size

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14
Q

sterling forces of kidney

A

pressure differential between hydrostatic and oncotic

Hyrdro is higher in glomerulues, lower in bowmans so, fluid flows into nephron

Osmo is higher in Bowmans, opposes fluid into nephron

Hydrostatic overall greater than osmotic

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15
Q

secretion

A

salt, acid, water, base, urea move into tubule

removes when there is XS in blood or large waste

moves from blood to filtrate

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16
Q

reabsorbtion

A

solutes from filtrate to blood

take up for use (glucose, vitamins, amino acids)

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16
Q

PCT

A

reabsorbs glucose, amino acids, salt, water, vitamins

interstitium is where solutes enter and are picked up by vasa recta for return to blood

excretes H, K, ammonia, urea

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16
Q

Loop of Henle

A

descending to medulla to ascending

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17
Q

descending LOH

A

water moves, medulla increases osmolarity the deeper in

Max reabs. and conservation of water

more concentrated in interstitium allows water to move out of tubule, into interstitium then blood

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18
Q

ascending LOH

A

salts, uses the decreasing medulla osmolarity

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19
Q

diluting segment

A

thicker LOH, cells have more mitochondria so they can use active transport to reabsorb NaCl

hypotonic to filtrate

produces more dilute urine

20
Q

DCT

A

responds to aldosterone, increases Na reabsorption and water follows

concentraties urine, decreases volume and produces waste

21
Q

collecting duct

A

responds to aldosterone and ADH to increase water reabsorption and concentrates urine output

increases permeability to increase water reabsorption

filtrate leaves and collects at renal pelvis then moves to ureter

22
Q

countercurrent multiplier

A

filtrate flow through LOH is opposite of blood through vasa recta

exposes filtrate to hypertonic blood and maximizes water reabsorption

23
excretory system
osmolarity gradients and permeability aids filtering, secretion, and reabsorption controls BP, osmolarity, and acid base balance
24
aldosterone
secreted by cortex when BP is low, increases excretion of K/H
25
how does aldosterone increase BP
when BP is low, juxtaglomerular cells release renin renin cleaves angiotensinogen ace converts angiotensin 1 to angiotensin 2 aldosterone is released from cortex aldosterone alters DCT and collecting ducts NA absorption and water flows with is DOES NOT change osmolarity - increases BV and BP
26
ADH
released by posterior pituitary when blood osmolarity is high, increases water reabsorption and decreases osmolarity
27
How does ADG alter blood osmolarity
changes permeability of collecting duct to increase water reabsorption by making junctions leaky interstitium is hypertonic to filtrate so water is reabsorbed from tubule inhib. by caffeine and alcohol
28
how does ADH raise BP
constricts afferent arteriole to decrease pressure of blood at glomeruli and release renin to increase BP
29
osmoregulation
osmotic pressure draws water in, oncotic pressure is the pressure of dissolved proteins controlled by kidneys to regulate filtering and secretions
30
what happens when osmolarity is low
excrete excess water and reabsorb solutes
31
How to alter pH
increase RR to increase pH: removing CO2, so converts H/HCO3 back to CO2 kidneys can excrete more H+ and increase bicarbonate reabsorption to increase pH
32
layers of skin
hypodermis (subq) dermis epidermis derived from ectoderm
33
strata layers of epidermis
basale, spinosum, granulosum, lucidum, corneum
34
epidermis basale
deep, stem cell, proliferation of keratinocytes
35
spinosum
connected, langerhans
36
granulosum
keratinocytes die and loose nucleil
37
lucidum
thick, hairless
38
corneum
flattened keratinocytes
39
keratin
protects body from injury, water, and pathogens
40
callus
XS keratin where there is repeated strain
41
melanocytes
from neural crest cells melanin protects from DNA damage due to UV and is darker when more active
42
langerhans
macrophage in spinosum, represent antigen to T cells
43
Dermis layer
Papillary: upper, loose connective Reticular: dense has sweat glands, vessels, hair follicles, sensory receptors
44
Merkel cells
at epi-dermal junction deep pressure and texture sensation
45
Free nerve cells
response to pain
46
Meissener cells
light touch
47
ruffini cells
stretch
48
pacinian cells
deep pressure and vibration
49
hypodermis
connective, skin to body, fat and fibrous