Chapter 2 Flashcards
(68 cards)
Diploid
2n, cells have two copies of each chromosome
Haploid
n, one copy
Interphase
G1, S, G2
DNA is uncoiled and in the form of chromatin
G1 restriction point
DNA is checked for quality, must be passed to move on to S stage
G1 (mitosis)
Presynthetic gap, cells create organelles for energy and protein production, and increase their size
S Stage (mitosis)
Synthesis, DNA is replicated
Strands of DNA (chromatids) are held together at the centromere
G2 (mitosis)
Postsynthetic gap, further cell growth and replication of organelles.
Has quality check point for proper replication, and enough organelles/ cytoplasm
M stage (Mitosis)
Mitosis and cytokinesis occur
G0
offbranch of G1, cell performs functions without preparing for divisions
P53
role in checkpoints for G1 to S and G2 to M
Cyclins and CDKs
Rise and fall during the cell cycle. Cyclins bind to CDKs and phosphorylating and activating transcription factors for the next stage of the cell cycle
Somatic Cells
When mitosis produces 2 genetically identical diploid daughter cells from a single cell
Phases of mitosis
Prophase, Metaphase, Anaphase, telephase
Prophase (mitosis)
Chromatin condenses into chromosomes, nuclear membrane dissolves and nucleoli disappear, centrioles migrate to opposite sides of the cell. Spindle apparatus begins to form.
Kinetochore of each chromosome is contacted by a spindle fiber
Metephase
Chromosomes line up along the metaphase plate
uses spindle and kinetechore
Centriole pairs on opposite sides
Anaphase
Sister chromatids are separated and pulled to opposite poles
Centromere splits
Telophase
Nuclear membrane reforms, spindle apparatus disappears. Cytosol and organelles re split between the two daughter cells through cytokinesis
Chromosomes uncoil
Meiosis
In gametes, produces up for 4 non identical haploid sex cells
1 round of replication and 2 round of divisions (reductional and equational divisions)
Meiosis I
Homologous pairs of chromosomes are separated from each other
Homologues
Chromosomes are given the same number but are opposite parental origin
Prophase I
chromosomes condense, nuclear membrane dissolves, nucleoli disappear
Spindle forms
**homologues intertwine – synapsis occurs
Tetrad
Homologues intertwined in prophase 1 of meiosis, can cross over
has 4 chromatids
Crossing over
Tetrads
Genetic material of one chromatid is exchanged for material of another chromatid in the homologous chromosome
Accounts for mendels second law of independent assortment
Metaphase 1 (meiosis)
Homologous chromosomes (tetrads) line up on opposite sides of the metaphase plate
spindle attaches kinetochore
** has only one fiber attatched